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Lgals4 Gene Detail
Summary
  • Symbol
    Lgals4
  • Name
    lectin, galactose binding, soluble 4
  • Synonyms
    galectin-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:107536
    NCBI Gene: 16855
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28533559-28541128 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 16.94 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    392 from dbSNP Build 142
  • Strain Annotations
    16
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107536
 protein coding gene Chr7:28533279-28541133 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031964
 protein coding gene Chr7:27690121-27698882 (+)
A/J MGP_AJ_G0031942
 protein coding gene Chr7:26985215-26994193 (+)
AKR/J MGP_AKRJ_G0031874
 protein coding gene Chr7:27678758-27694224 (+)
BALB/cJ MGP_BALBcJ_G0031949
 protein coding gene Chr7:27141783-27150003 (+)
C3H/HeJ MGP_C3HHeJ_G0031668
 protein coding gene Chr7:28086140-28087846 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032413
 protein coding gene Chr7:28585587-28595002 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029465
 protein coding gene Chr7:28044467-28059238 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0031786
 protein coding gene Chr7:26734912-26742662 (+)
FVB/NJ MGP_FVBNJ_G0031743
 protein coding gene Chr7:26818369-26826392 (+)
LP/J MGP_LPJ_G0031866
 protein coding gene Chr7:28005284-28014309 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031779
 protein coding gene Chr7:29326284-29335768 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032443
 protein coding gene Chr7:27160362-27168170 (+)
PWK/PhJ MGP_PWKPhJ_G0030728
 protein coding gene Chr7:21760085-21770402 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030561
 protein coding gene Chr7:18182506-18190220 (+)
WSB/EiJ MGP_WSBEiJ_G0031112
 protein coding gene Chr7:27528250-27536735 (+)



Homology
more
  • Human Ortholog
    LGALS4, galectin 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LGALS4, galectin 4
  • Synonyms
    GAL4, L36LBP
  • Links
    NCBI Gene ID: 3960
    neXtProt AC: NX_P56470
    UniProt: P56470

  • Chr Location
    19q13.2; chr19:38801671-38812945 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    780
  • Tissues
    41
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16855 NCBI Gene Model | MGI Sequence Detail 7570 C57BL/6J ±  kb
transcript NR_182022 RefSeq | MGI Sequence Detail 1180 ZRU/MplStud  
polypeptide Q8K419 UniProt | EBI | MGI Sequence Detail 326 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 1
    cDNA 16
    Primer pair 3

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-36106
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:33381 Jonassen T, et al., Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. (Correction appears in Arch Biochem Biophys 1996; 335(1):227). Arch Biochem Biophys. 1996 Jun 15;330(2):285-9
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory