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Tbca Gene Detail
Summary
  • Symbol
    Tbca
  • Name
    tubulin cofactor A
  • Synonyms
    co-chaperonin associated with a- & b-tubulin, cofactor A, Tbca13
  • Feature Type
    protein coding gene
  • IDs
    MGI:107549
    NCBI Gene: 21371
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:94925428-94979431 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 49.22 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1213 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107549
 protein coding gene Chr13:94925418-94979431 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020834
 protein coding gene Chr13:96216266-96281560 (+)
A/J MGP_AJ_G0020788
 protein coding gene Chr13:92614411-92668789 (+)
AKR/J MGP_AKRJ_G0020762
 protein coding gene Chr13:95444973-95502335 (+)
BALB/cJ MGP_BALBcJ_G0020785
 protein coding gene Chr13:93294927-93349245 (+)
C3H/HeJ MGP_C3HHeJ_G0020578
 protein coding gene Chr13:95153042-95206916 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021221
 protein coding gene Chr13:99140759-99199088 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018790
 protein coding gene Chr13:88449565-88503493 (+)
CAST/EiJ MGP_CASTEiJ_G0020097
 protein coding gene Chr13:94417284-94472140 (+)
CBA/J MGP_CBAJ_G0020537
 protein coding gene Chr13:103082679-103142931 (+)
DBA/2J MGP_DBA2J_G0020662
 protein coding gene Chr13:92405821-92460030 (+)
FVB/NJ MGP_FVBNJ_G0020643
 protein coding gene Chr13:91187008-91242097 (+)
LP/J MGP_LPJ_G0020737
 protein coding gene Chr13:96322584-96382151 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020671
 protein coding gene Chr13:103533760-103593488 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021261
 protein coding gene Chr13:94845152-94900546 (+)
PWK/PhJ MGP_PWKPhJ_G0019849
 protein coding gene Chr13:91125878-91181726 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019673
 protein coding gene Chr13:91097288-91155067 (+)
WSB/EiJ MGP_WSBEiJ_G0020154
 protein coding gene Chr13:95328722-95385188 (+)



Homology
more
  • Human Ortholog
    TBCA, tubulin folding cofactor A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TBCA, tubulin folding cofactor A
  • Links
    NCBI Gene ID: 6902
    neXtProt AC: NX_O75347
    UniProt: O75347

  • Chr Location
    5q14.1; chr5:77691166-77868780 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    48
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    43
  • Targeted
    3
  • Genomic Mutations
    1 involving Tbca
  • Find Mice (IMSR)
    20 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    5
  • cDNA Data
    37
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21371 NCBI Gene Model | MGI Sequence Detail 54004 C57BL/6J ±  kb
transcript NM_009321 RefSeq | MGI Sequence Detail 550 C57BL/6  
polypeptide P48428 UniProt | EBI | MGI Sequence Detail 108 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36120
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:189827 Nolasco S, et al., The expression of tubulin cofactor A (TBCA) is regulated by a noncoding antisense Tbca RNA during testis maturation. PLoS One. 2012;7(8):e42536
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory