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Dync1i1 Gene Detail
Summary
  • Symbol
    Dync1i1
  • Name
    dynein cytoplasmic 1 intermediate chain 1
  • Synonyms
    DIC, Dncic1, IC74
  • Feature Type
    protein coding gene
  • IDs
    MGI:107743
    NCBI Gene: 13426
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:5725772-6028030 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 2.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    8364 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107743
 protein coding gene Chr6:5725639-6028039 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030437
 protein coding gene Chr6:2588633-2905746 (+)
A/J MGP_AJ_G0030410
 protein coding gene Chr6:2487195-2784918 (+)
AKR/J MGP_AKRJ_G0030337
 protein coding gene Chr6:2553328-2857853 (+)
BALB/cJ MGP_BALBcJ_G0030419
 protein coding gene Chr6:2453272-2754379 (+)
C3H/HeJ MGP_C3HHeJ_G0030133
 protein coding gene Chr6:2533720-2845355 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030874
 protein coding gene Chr6:2645085-2968898 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028085
 protein coding gene Chr6:2156921-2462377 (+)
CAST/EiJ MGP_CASTEiJ_G0029534
 protein coding gene Chr6:2522528-2838348 (+)
CBA/J MGP_CBAJ_G0030111
 protein coding gene Chr6:2756613-3121280 (+)
DBA/2J MGP_DBA2J_G0030255
 protein coding gene Chr6:2437780-2740393 (+)
FVB/NJ MGP_FVBNJ_G0030209
 protein coding gene Chr6:2425267-2721753 (+)
LP/J MGP_LPJ_G0030342
 protein coding gene Chr6:2535325-2849257 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030245
 protein coding gene Chr6:2807884-3138287 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030904
 protein coding gene Chr6:2509923-2822559 (+)
PWK/PhJ MGP_PWKPhJ_G0029249
 protein coding gene Chr6:2384978-2686705 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029085
 protein coding gene Chr6:2557450-2876938 (+)
WSB/EiJ MGP_WSBEiJ_G0029611
 protein coding gene Chr6:2504351-2823714 (+)



Homology
more
  • Human Ortholog
    DYNC1I1, dynein cytoplasmic 1 intermediate chain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DYNC1I1, dynein cytoplasmic 1 intermediate chain 1
  • Synonyms
    DNCI1, DNCIC1
  • Links
    NCBI Gene ID: 1780
    neXtProt AC: NX_O14576
    UniProt: O14576

  • Chr Location
    7q21.3; chr7:95772506-96110322 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1041
  • Tissues
    92
  • cDNA Data
    22
  • Literature Summary
    21
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13426 NCBI Gene Model | MGI Sequence Detail 302259 C57BL/6J ±  kb
transcript NM_001409609 RefSeq | MGI Sequence Detail 2775 ZRU/MplStud  
polypeptide O88485 UniProt | EBI | MGI Sequence Detail 628 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 23
    Primer pair 11
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36319
References
more
  • Summaries
    All 68
    Developmental Gene Expression 21
    Gene Ontology 13
    Phenotypes 8
  • Earliest
    J:34934 Vaughan KT, et al., Multiple mouse chromosomal loci for dynein-based motility. Genomics. 1996 Aug 15;36(1):29-38
  • Latest
    J:334512 He S, et al., Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory