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Tpd52 Gene Detail
Summary
  • Symbol
    Tpd52
  • Name
    tumor protein D52
  • Synonyms
    mD52
  • Feature Type
    protein coding gene
  • IDs
    MGI:107749
    NCBI Gene: 21985
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:8991590-9069824 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 2.23 cM, cytoband A1-A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2933 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107749
 protein coding gene Chr3:8990653-9069824 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027055
 protein coding gene Chr3:5781859-5864502 (-)
A/J MGP_AJ_G0027019
 protein coding gene Chr3:6012717-6102233 (-)
AKR/J MGP_AKRJ_G0026989
 protein coding gene Chr3:5894640-5986738 (-)
BALB/cJ MGP_BALBcJ_G0027028
 protein coding gene Chr3:5738376-5823774 (-)
C3H/HeJ MGP_C3HHeJ_G0026768
 protein coding gene Chr3:6170421-6269033 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027472
 protein coding gene Chr3:6394850-6483094 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024834
 protein coding gene Chr3:4997143-5081320 (-)
CAST/EiJ MGP_CASTEiJ_G0026226
 protein coding gene Chr3:6199724-6287959 (-)
CBA/J MGP_CBAJ_G0026746
 protein coding gene Chr3:6317120-6408259 (-)
DBA/2J MGP_DBA2J_G0026882
 protein coding gene Chr3:5611831-5690144 (-)
FVB/NJ MGP_FVBNJ_G0026849
 protein coding gene Chr3:5503449-5584169 (-)
LP/J MGP_LPJ_G0026992
 protein coding gene Chr3:6296234-6381864 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026869
 protein coding gene Chr3:7438524-7524120 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027532
 protein coding gene Chr3:5741272-5831000 (-)
PWK/PhJ MGP_PWKPhJ_G0025961
 protein coding gene Chr3:5818279-5899890 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025764
 protein coding gene Chr3:5877918-5961773 (-)
WSB/EiJ MGP_WSBEiJ_G0026297
 protein coding gene Chr3:5745904-5825532 (-)



Homology
more
  • Human Ortholog
    TPD52, tumor protein D52
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TPD52, tumor protein D52
  • Synonyms
    D52, hD52, N8L, PC-1, PrLZ
  • Links
    NCBI Gene ID: 7163
    neXtProt AC: NX_P55327
    UniProt: P55327

  • Chr Location
    8q21.13; chr8:80031082-80231232 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    988
  • Tissues
    53
  • cDNA Data
    221
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 21985 NCBI Gene Model | MGI Sequence Detail 78235 C57BL/6J ±  kb
transcript NM_001357072 RefSeq | MGI Sequence Detail 5712 C57BL/6  
polypeptide Q62393 UniProt | EBI | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 223
    cDNA 222
    Other 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-36325, MGI:2139619
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:34618 Byrne JA, et al., Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52). Genomics. 1996 Aug 1;35(3):523-32
  • Latest
    J:243218 Hooper JE, et al., Systems biology of facial development: contributions of ectoderm and mesenchyme. Dev Biol. 2017 Jun 01;426(1):97-114
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory