About   Help   FAQ
Aup1 Gene Detail
Summary
  • Symbol
    Aup1
  • Name
    ancient ubiquitous protein 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:107789
    NCBI Gene: 11993
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:83031483-83034663 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 35.94 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107789
 protein coding gene Chr6:83031483-83034789 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030912
 protein coding gene Chr6:84058204-84061491 (+)
A/J MGP_AJ_G0030881
 protein coding gene Chr6:80844870-80848157 (+)
AKR/J MGP_AKRJ_G0030809
 protein coding gene Chr6:83174325-83177612 (+)
BALB/cJ MGP_BALBcJ_G0030891
 protein coding gene Chr6:80857825-80861112 (+)
C3H/HeJ MGP_C3HHeJ_G0030819
 protein coding gene Chr6:101206044-101209331 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031351
 protein coding gene Chr6:86337571-86340858 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028537
 protein coding gene Chr6:79203543-79206829 (+)
CAST/EiJ MGP_CASTEiJ_G0030000
 protein coding gene Chr6:83174412-83177696 (+)
CBA/J MGP_CBAJ_G0030578
 protein coding gene Chr6:89749844-89753131 (+)
DBA/2J MGP_DBA2J_G0030731
 protein coding gene Chr6:80164479-80167766 (+)
FVB/NJ MGP_FVBNJ_G0030684
 protein coding gene Chr6:79372196-79375483 (+)
LP/J MGP_LPJ_G0030810
 protein coding gene Chr6:84052104-84055391 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030720
 protein coding gene Chr6:94054602-94057889 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031375
 protein coding gene Chr6:82987080-82990364 (+)
PWK/PhJ MGP_PWKPhJ_G0029715
 protein coding gene Chr6:79056680-79060056 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029543
 protein coding gene Chr6:81833580-81836862 (+)
WSB/EiJ MGP_WSBEiJ_G0030081
 protein coding gene Chr6:83426661-83429948 (+)



Homology
more
  • Human Ortholog
    AUP1, AUP1 lipid droplet regulating VLDL assembly factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AUP1, AUP1 lipid droplet regulating VLDL assembly factor
  • Links
    NCBI Gene ID: 550
    neXtProt AC: NX_Q9Y679
    UniProt: Q9Y679

  • Chr Location
    2p13.1; chr2:74526645-74529760 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    747
  • Tissues
    28
  • cDNA Data
    162
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11993 NCBI Gene Model | MGI Sequence Detail 3181 C57BL/6J ±  kb
transcript NR_125891 RefSeq | MGI Sequence Detail 1721 ZRU/MplStud  
polypeptide P70295 UniProt | EBI | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 164
    Genomic 2
    cDNA 162

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36366, MGI:2141369
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:35452 Jang W, et al., Aup1, a novel gene on mouse chromosome 6 and human chromosome 2p13. Genomics. 1996 Sep 1;36(2):366-8
  • Latest
    J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory