D6Wsu163e Gene Detail

Summary

• Symbol
  D6Wsu163e
• Name
  DNA segment, Chr 6, Wayne State University 163, expressed

• Feature Type
  protein coding gene
• IDs
  MGI:107893
  NCBI Gene: 28040
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr6:126916938-126952667 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 61.92 cM
• Mapping Data
  4 experiments

Strain
Comparison

• SNPs within 2kb
  871 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_107893	protein coding gene	Chr6:126916925-126952930 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031309	protein coding gene	Chr6:130415932-130454813 (+)
A/J	MGP_AJ_G0031280	protein coding gene	Chr6:125464357-125500136 (+)
AKR/J	MGP_AKRJ_G0031208	protein coding gene	Chr6:128850799-128890315 (+)
BALB/cJ	MGP_BALBcJ_G0031287	protein coding gene	Chr6:125026235-125060546 (+)
C3H/HeJ	MGP_C3HHeJ_G0031011	protein coding gene	Chr6:128976582-129011382 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0031744	protein coding gene	Chr6:133820423-133858395 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028892	protein coding gene	Chr6:122634719-122671582 (+)
CAST/EiJ	MGP_CASTEiJ_G0030392	protein coding gene	Chr6:129167621-129205445 (+)
CBA/J	MGP_CBAJ_G0030972	protein coding gene	Chr6:138956827-138997048 (+)
DBA/2J	MGP_DBA2J_G0031128	protein coding gene	Chr6:124349636-124384279 (+)
FVB/NJ	MGP_FVBNJ_G0031077	protein coding gene	Chr6:123278674-123312979 (+)
LP/J	MGP_LPJ_G0031208	protein coding gene	Chr6:130532277-130566595 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031116	protein coding gene	Chr6:142930321-142965617 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031779	protein coding gene	Chr6:128810296-128845739 (+)
PWK/PhJ	MGP_PWKPhJ_G0030107	protein coding gene	Chr6:122616948-122651472 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0029936	protein coding gene	Chr6:126878651-126912534 (+)
WSB/EiJ	MGP_WSBEiJ_G0030477	protein coding gene	Chr6:129170747-129204749 (+)

Homology

• Human Ortholog
  FERRY3, FERRY endosomal RAB5 effector complex subunit 3

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FERRY3, FERRY endosomal RAB5 effector complex subunit 3
  
• Synonyms
  C12orf4, Fy-3, MRT66
• Links
  HGNC:1184

  NCBI Gene ID: 57102

  neXtProt AC: NX_Q9NQ89

  UniProt: Q9NQ89

  
  
• Chr Location
  12p13.32; chr12:4487735-4538508 (-)  GRCh38

---

• MGI Vertebrate Homology
  D6Wsu163e stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: FERRY3
• Gene Tree
  D6Wsu163e
  

Human Diseases

• Diseases
  1 with human FERRY3 associations

				Human Disease	Mouse Models
				autosomal recessive intellectual developmental disorder 66 IDs autosomal recessive intellectual developmental disorder 66       DOID:0081227 OMIM:618221

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  18 phenotypes from 1 allele in 1 genetic background
  11 phenotype references
  

• All Mutations and Alleles
  8
• Endonuclease-mediated
  2
• Gene trapped
  2
• Targeted
  4
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  30 strains or lines available
• Comparison Matrix
  Gene Expression + Phenotype

Gene Ontology
(GO)
Classifications

• All GO Annotations
  10
• GO References
  5

Expression

• Assay Results
  712
• Tissues
  2
• cDNA Data
  153
• Literature Summary
  1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  52
• RefSeq
  8
• UniProt
  3
• CCDS
  CCDS20560.1

• Ensembl
  ENSMUSG00000030347 (Evidence)
• NCBI Gene
  28040

Representative Sequences			Length	Strain/Species
genomic	28040	NCBI Gene Model | MGI Sequence Detail	35730	C57BL/6J
transcript	NM_001410642	RefSeq | MGI Sequence Detail	2513	C57BL/6
polypeptide	Q91YN0	UniProt | EBI | MGI Sequence Detail	552	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000060103 protein C12orf4
  (term hierarchy)
• InterPro Domains
  IPR019311 Protein of unknown function DUF2362
• GlyGen
  Q91YN0 2 sites, 2 N-linked glycans (2 sites)

Molecular
Reagents

• All nucleic 155

  cDNA 154

  Primer pair 1

  
  

  Microarray probesets 3

Other
Accession IDs

MGD-MRK-36471

References

• Summaries
  All 39

  Developmental Gene Expression 1

  Gene Ontology 5

  Phenotypes 11
• Earliest
  J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
• Latest
  J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for D6Wsu163e:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr59015	Chr6:126916920-126916951 (+)	-2 bp
Tssr59016	Chr6:126916956-126916967 (+)	24 bp