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Erh Gene Detail
Summary
  • Symbol
    Erh
  • Name
    ERH mRNA splicing and mitosis factor
  • Synonyms
    Mer, Prei1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108089
    NCBI Gene: 13877
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:80680799-80690616 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 36.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    276 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108089
 protein coding gene Chr12:80680796-80691115 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019890
 protein coding gene Chr12:81015049-81025676 (-)
A/J MGP_AJ_G0019848
 protein coding gene Chr12:78074089-78084483 (-)
AKR/J MGP_AKRJ_G0019823
 protein coding gene Chr12:80208798-80218837 (-)
BALB/cJ MGP_BALBcJ_G0019827
 protein coding gene Chr12:78327542-78337753 (-)
C3H/HeJ MGP_C3HHeJ_G0019633
 protein coding gene Chr12:80679708-80689157 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020279
 protein coding gene Chr12:83382635-83395466 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017898
 protein coding gene Chr12:75066854-75078850 (-)
CAST/EiJ MGP_CASTEiJ_G0019183
 protein coding gene Chr12:75531825-75544424 (-)
CBA/J MGP_CBAJ_G0019604
 protein coding gene Chr12:86649840-86661021 (-)
DBA/2J MGP_DBA2J_G0019719
 protein coding gene Chr12:77685061-77696769 (-)
FVB/NJ MGP_FVBNJ_G0019705
 protein coding gene Chr12:76508685-76519293 (-)
LP/J MGP_LPJ_G0019791
 protein coding gene Chr12:80943928-80954221 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019744
 protein coding gene Chr12:89652030-89663907 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020314
 protein coding gene Chr12:79734913-79744522 (-)
PWK/PhJ MGP_PWKPhJ_G0018949
 protein coding gene Chr12:72076543-72087465 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018743
 protein coding gene Chr12:74241895-74257439 (-)
WSB/EiJ MGP_WSBEiJ_G0019236
 protein coding gene Chr12:80377689-80387778 (-)



Homology
more
  • Human Ortholog
    ERH, ERH mRNA splicing and mitosis factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERH, ERH mRNA splicing and mitosis factor
  • Synonyms
    DROER
  • Links
    NCBI Gene ID: 2079
    neXtProt AC: NX_P84090
    UniProt: P84090

  • Chr Location
    14q24.1; chr14:69380128-69398299 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    26
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    21
  • Targeted
    3
  • Genomic Mutations
    1 involving Erh
  • Find Mice (IMSR)
    26 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    841
  • Tissues
    103
  • cDNA Data
    12
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13877 NCBI Gene Model | MGI Sequence Detail 9818 C57BL/6J ±  kb
transcript NM_001409595 RefSeq | MGI Sequence Detail 964 C57BL/6  
polypeptide P84089 UniProt | EBI | MGI Sequence Detail 104 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 12
    Primer pair 2
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-29054, MGD-MRK-37126, MGI:104901
References
more
  • Summaries
    All 38
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:16710 Temeles GL, et al., Expression patterns of novel genes during mouse preimplantation embryogenesis. Mol Reprod Dev. 1994 Feb;37(2):121-9
  • Latest
    J:225471 Sutherland JM, et al., RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus. FASEB J. 2015 Jul;29(7):2759-68
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory