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Acat3 Gene Detail
Summary
  • Symbol
    Acat3
  • Name
    acetyl-Coenzyme A acetyltransferase 3
  • Synonyms
    ACTL
  • Feature Type
    protein coding gene
  • IDs
    MGI:109182
    NCBI Gene: 224530
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
  • Candidate for QTL
    4 QTL
Location &
Maps
more
  • Sequence Map
    Chr17:13142720-13159482 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 8.72 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    467 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109182
 protein coding gene Chr17:13142700-13159487 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023155
 protein coding gene Chr17:10594849-10615497 (-)
A/J MGP_AJ_G0023123
 protein coding gene Chr17:10425424-10446409 (-)
AKR/J MGP_AKRJ_G0023087
 protein coding gene Chr17:10261281-10294924 (-)
BALB/cJ MGP_BALBcJ_G0023123
 protein coding gene Chr17:10208155-10228954 (-)
C3H/HeJ MGP_C3HHeJ_G0022886
 protein coding gene Chr17:10505212-10527188 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023566
 protein coding gene Chr17:10995883-11024991 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021042
 protein coding gene Chr17:4010036-4026002 (+)
CAST/EiJ MGP_CASTEiJ_G0022400
 protein coding gene Chr17:10590263-10595601 (-)
CBA/J MGP_CBAJ_G0022858
 protein coding gene Chr17:11417907-11468839 (-)
DBA/2J MGP_DBA2J_G0022991
 protein coding gene Chr17:10062301-10088210 (-)
FVB/NJ MGP_FVBNJ_G0022961
 protein coding gene Chr17:9999142-10016241 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0022980
 protein coding gene Chr17:11014540-11073766 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023592
 protein coding gene Chr17:10530172-10550930 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0021978
 protein coding gene Chr17:9960658-9980731 (-)
WSB/EiJ MGP_WSBEiJ_G0022457
 protein coding gene Chr17:10843157-10868563 (-)



Homology
more
  • Human Ortholog
    ACAT2, acetyl-CoA acetyltransferase 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACAT2, acetyl-CoA acetyltransferase 2
  • Links
    NCBI Gene ID: 39
    neXtProt AC: NX_Q9BWD1
    UniProt: Q9BWD1

  • Chr Location
    6q25.3; chr6:159762045-159779112 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ACAT2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    869
  • Tissues
    18
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 224530 NCBI Gene Model | MGI Sequence Detail 16763 C57BL/6J ±  kb
transcript NM_001410277 RefSeq | MGI Sequence Detail 2119 ZRU/MplStud  
polypeptide NP_694791 RefSeq | MGI Sequence Detail 397 ZRU/MplStud  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-38226
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:15561 Ashworth A, Two acetyl-CoA acetyltransferase genes located in the t-complex region of mouse chromosome 17 partially overlap the Tcp-1 and Tcp-1x genes. Genomics. 1993 Nov;18(2):195-8
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory