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Snap23
Gene Detail
Symbol

Name
ID
Snap23
synaptosomal-associated protein 23
MGI:109356
Synonyms
SNAP-23, Sndt, Syndet
Feature Type
protein coding gene
Genetic Map
Chromosome 2
60.37 cM, cytoband E5
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr2:120567671-120601255 bp, + strand
From VEGA annotation of GRCm38

  33585 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37857  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SNAP23
Gene Tree: Snap23

Human
homologs
SNAP23, synaptosomal-associated protein, 23kDa
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 8773
neXtProt AC: NX_O00161

Human Synonyms: HsT17016, SNAP-23, SNAP23A, SNAP23B

Human Chr (Location): 15q14; chr15:42491244-42533061 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(50) : Gene trapped(45) Targeted(5)
 
Mice homozygous for a knock-out allele exhibit lethality prior to E3.5.
 
Interactions
Snap23 interacts with 276 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (39 annotations)
Process exocytosis, histamine secretion by mast cell, ...
Component azurophil granule, cell, ...
Function protein binding, SNAP receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase snap23    NEW 
Molecular
reagents
All nucleic(15) Genomic(1) cDNA(13) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000015619 (Evidence)
Ensembl Gene Model ENSMUSG00000027287 (Evidence)
Entrez Gene 20619 (Evidence)
DFCI TC1661259, TC1575721, TC1696251
DoTS DT.87069329, DT.101392911, DT.101349767, DT.94185301, DT.94185306
NIA Mouse Gene Index U361075, U042350
Consensus CDS Project CCDS16622.1, CCDS50681.1
International Mouse Phenotyping Consortium Status Snap23
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015619 VEGA Gene Model | MGI Sequence Detail 33585 C57BL/6J ±  kb
transcript OTTMUST00000037102 VEGA | MGI Sequence Detail 2730 Not Applicable 
polypeptide OTTMUSP00000016634 VEGA | MGI Sequence Detail 221 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(14) UniProt(6)
Polymorphisms
RFLP(1) : SNPs within 2kb(167 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000928 SNAP-25
InterPro IPR000727 Target SNARE coiled-coil domain
Protein Ontology PR:000015311 synaptosomal-associated protein 23
References
(Earliest) J:38843 Wang G, et al., Syndet is a novel SNAP-25 related protein expressed in many tissues. J Cell Sci. 1997 Feb;110(Pt 4):505-13
(Latest) J:217856 Corradini I, et al., Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs. Cereb Cortex. 2014 Feb;24(2):364-76
All references(55)
Other
accession IDs
MGD-MRK-38401, MGI:2138756

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory