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Ly6g Gene Detail
Summary
  • Symbol
    Ly6g
  • Name
    lymphocyte antigen 6 family member G
  • Synonyms
    Gr-1, Gr1, Ly-6G
  • Feature Type
    protein coding gene
  • IDs
    MGI:109440
    NCBI Gene: 546644
  • Member of
    Ly6 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75027110-75030977 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.29 cM, cytoband E1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    218 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109440
 protein coding gene Chr15:75027089-75030977 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021949
 protein coding gene Chr15:75047536-75049968 (+)
A/J MGP_AJ_G0021904
 protein coding gene Chr15:72368052-72370478 (+)
AKR/J MGP_AKRJ_G0021888
 protein coding gene Chr15:74291560-74293992 (+)
BALB/cJ MGP_BALBcJ_G0021913
 protein coding gene Chr15:72357494-72359484 (+)
C3H/HeJ MGP_C3HHeJ_G0021685
 protein coding gene Chr15:74393818-74398611 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022356
 protein coding gene Chr15:77927632-77931517 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019888
 protein coding gene Chr15:69107022-69109427 (+)
CAST/EiJ MGP_CASTEiJ_G0021207
 protein coding gene Chr15:75130140-75132130 (+)
CBA/J MGP_CBAJ_G0021652
 protein coding gene Chr15:80417686-80420112 (+)
DBA/2J MGP_DBA2J_G0021777
 protein coding gene Chr15:71941318-71943750 (+)
FVB/NJ MGP_FVBNJ_G0021758
 protein coding gene Chr15:70953622-70955618 (+)
LP/J MGP_LPJ_G0021850
 protein coding gene Chr15:75150747-75153179 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021782
 protein coding gene Chr15:85698747-85700737 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022377
 protein coding gene Chr15:74585220-74702022 (+)
PWK/PhJ MGP_PWKPhJ_G0020948
 protein coding gene Chr15:71957710-71959707 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020787
 protein coding gene Chr15:74324385-74326391 (+)
WSB/EiJ MGP_WSBEiJ_G0021260
 protein coding gene Chr15:74634567-74636557 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    60 phenotype references
Mice homozygous for a Cre-knock-in/null allele show normal leukocyte cellularity in all measured organs. Deficient neutrophils were functionally normal in vitro and in multiple models of sterile or infectious inflammation in vivo.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    7
  • Literature Summary
    17
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 546644 NCBI Gene Model | MGI Sequence Detail 3868 C57BL/6J ±  kb
transcript NM_001310438 RefSeq | MGI Sequence Detail 922 C57BL/6  
polypeptide P35461 UniProt | EBI | MGI Sequence Detail 134 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    Genomic 1
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-38485
References
more
  • Summaries
    All 126
    Developmental Gene Expression 17
    Diseases 1
    Gene Ontology 11
    Phenotypes 60
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:348590 Passino R, et al., Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration. Cell Rep. 2024 Mar 14;43(3):113931
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory