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Kifc1 Gene Detail
Summary
  • Symbol
    Kifc1
  • Name
    kinesin family member C1
  • Synonyms
    Gm4137, HSET, Kifc5a, kinesin family c-terminal 5A, KNSL2, Knsl2a, Tctex-7, Tctex7, Tctex7a, Tctex-7A
  • Feature Type
    protein coding gene
  • IDs
    MGI:109596
    NCBI Gene: 100502766
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:34094640-34109607 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109596
 protein coding gene Chr17:34094633-34109635 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023409
 protein coding gene Chr17:26141883-26162335 (+)
A/J MGP_AJ_G0023501
 protein coding gene Chr17:32650327-32673051 (-)
AKR/J MGP_AKRJ_G0023467
 protein coding gene Chr17:33036679-33048934 (-)
BALB/cJ MGP_BALBcJ_G0023504
 protein coding gene Chr17:32801000-32805293 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0023813
 protein coding gene Chr17:27231536-27253569 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022633
 protein coding gene Chr17:25785828-25792440 (+)
CBA/J MGP_CBAJ_G0023243
 protein coding gene Chr17:36479999-36517086 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0023207
 protein coding gene Chr17:24695338-24702342 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0023362
 protein coding gene Chr17:35553491-35570476 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023855
 protein coding gene Chr17:25834151-25856348 (+)
PWK/PhJ MGP_PWKPhJ_G0022382
 protein coding gene Chr17:23698215-23715257 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022200
 protein coding gene Chr17:23868931-23879693 (+)
WSB/EiJ MGP_WSBEiJ_G0022828
 protein coding gene Chr17:33415229-33419264 (-)



Homology
more
  • Human Ortholog
    KIFC1, kinesin family member C1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIFC1, kinesin family member C1
  • Synonyms
    HSET, KNSL2
  • Links
    NCBI Gene ID: 3833
    neXtProt AC: NX_Q9BW19
    UniProt: Q9BW19

  • Chr Location
    6p21.32; chr6:33391461-33409896 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    905
  • Tissues
    110
  • cDNA Data
    31
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100502766 NCBI Gene Model | MGI Sequence Detail 14968 C57BL/6J ±  kb
transcript NM_001410588 RefSeq | MGI Sequence Detail 2344 ZRU/MplStud  
polypeptide Q9QWT9 UniProt | EBI | MGI Sequence Detail 674 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    Genomic 1
    cDNA 33
    Primer pair 2
    Other 2

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-14958, MGD-MRK-14959, MGD-MRK-14972, MGD-MRK-14973, MGD-MRK-39595, MGI:1346210, MGI:2137413, MGI:3782313, MGI:98651
References
more
  • Summaries
    All 46
    Developmental Gene Expression 7
    Gene Ontology 10
    Phenotypes 8
  • Earliest
    J:608 Ha H, et al., Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice. Dev Genet. 1991;12(4):318-32
  • Latest
    J:349895 Becker IC, et al., Cell cycle-dependent centrosome clustering precedes proplatelet formation. Sci Adv. 2024 Jun 21;10(25):eadl6153
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory