Cyp2g1 MGI Mouse Gene Detail - MGI:109612 - cytochrome P450, family 2, subfamily g, polypeptide 1

Symbol

Cyp2g1
Name

cytochrome P450, family 2, subfamily g, polypeptide 1

Feature Type

protein coding gene
IDs

MGI:109612
NCBI Gene: 13108
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr7:26508352-26520622 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 15.50 cM, cytoband A3
Mapping Data

1 experiment

SNPs within 2kb

355 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_109612	protein coding gene	Chr7:26508317-26520630 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031891	protein coding gene	Chr7:25390826-25403604 (+)
A/J	MGP_AJ_G0031870	protein coding gene	Chr7:24777560-24791315 (+)
AKR/J	MGP_AKRJ_G0031800	protein coding gene	Chr7:25398445-25413378 (+)
BALB/cJ	MGP_BALBcJ_G0031876	protein coding gene	Chr7:24971910-24994733 (+)
C3H/HeJ	MGP_C3HHeJ_G0031598	protein coding gene	Chr7:25816116-25834556 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032338	protein coding gene	Chr7:26243951-26265799 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029393	protein coding gene	Chr7:26069565-26081396 (+)
CAST/EiJ	MGP_CASTEiJ_G0030934	protein coding gene	Chr7:19097529-19112006 (+)
CBA/J	MGP_CBAJ_G0031563	protein coding gene	Chr7:27271974-27288698 (+)
DBA/2J	MGP_DBA2J_G0031715	protein coding gene	Chr7:24602635-24615599 (+)
FVB/NJ	MGP_FVBNJ_G0031670	protein coding gene	Chr7:24694175-24706501 (+)
LP/J	MGP_LPJ_G0031794	protein coding gene	Chr7:25664795-25678357 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031704	protein coding gene	Chr7:26930114-26941484 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032372	protein coding gene	Chr7:24982523-25004401 (+)
PWK/PhJ	MGP_PWKPhJ_G0030658	protein coding gene	Chr7:19553659-19567496 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030489	protein coding gene	Chr7:16111422-16123810 (+)
WSB/EiJ	MGP_WSBEiJ_G0031039	protein coding gene	Chr7:25258847-25297397 (+)

Human Ortholog

CYP2G1P, cytochrome P450 family 2 subfamily G member 1, pseudogene

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CYP2G1P, cytochrome P450 family 2 subfamily G member 1, pseudogene
Synonyms

CYP2G1, CYP2G2P, CYP2GP1
Links

HGNC:2633

NCBI Gene ID: 22952

UniProt: Q6ZSU1
Chr Location

19q13.2; chr19:40890826-40912357 (+) GRCh38

MGI Vertebrate Homology

Cyp2g1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CYP2G1P
Gene Tree

Cyp2g1

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Mutations/Alleles

1 with disease annotations

References

1 with disease annotations

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
7 phenotypes from multigenic genotypes
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

11
Endonuclease-mediated

4
Targeted

7
Genomic Mutations

2 involving Cyp2g1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

30 strains or lines available

Mice homozygous for disruptions in this gene display an essentially normal phenotype.

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All GO Annotations

7
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

728
Tissues

14
cDNA Data

13
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

30
RefSeq

2
UniProt

1
CCDS

CCDS21007.1

Ensembl

ENSMUSG00000049685 (Evidence)
NCBI Gene

13108

			Length	Strain/Species	Flank
genomic	13108	NCBI Gene Model \| MGI Sequence Detail	12271	C57BL/6J	± kb
transcript	NM_013809	RefSeq \| MGI Sequence Detail	1853	Not Specified
polypeptide	NP_038837	RefSeq \| MGI Sequence Detail	494	Not Specified

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UniProt

1 Sequence
EC

1.14.14.1
InterPro Domains

IPR001128 Cytochrome P450

IPR017972 Cytochrome P450, conserved site

IPR002401 Cytochrome P450, E-class, group I

IPR008067 Cytochrome P450, E-class, group I, CYP2A-like

IPR050182 Cytochrome P450 family 2

IPR036396 Cytochrome P450 superfamily

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All nucleic 15

cDNA 14

Primer pair 1

Microarray probesets 2

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MGD-MRK-39611

Summaries

All 34

Developmental Gene Expression 3

Diseases 1

Gene Ontology 1

Phenotypes 13
Earliest

J:39655 Hua Z, et al., cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase. Arch Biochem Biophys. 1997 Apr 15;340(2):208-14
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Cyp2g1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr65196	Chr7:26508305-26508334 (+)	-32 bp
Tssr65197	Chr7:26515740-26515762 (+)	7,399 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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