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Galr1 Gene Detail
Summary
  • Symbol
    Galr1
  • Name
    galanin receptor 1
  • Synonyms
    Galnr1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1096364
    NCBI Gene: 14427
  • Alliance
    gene page
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr18:82410621-82424902 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 55.78 cM, cytoband E3-E4
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    485 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1096364
 protein coding gene Chr18:82410505-82424902 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024600
 protein coding gene Chr18:83413560-83427845 (-)
A/J MGP_AJ_G0024567
 protein coding gene Chr18:79771847-79786126 (-)
AKR/J MGP_AKRJ_G0024538
 protein coding gene Chr18:82136849-82151130 (-)
BALB/cJ MGP_BALBcJ_G0024565
 protein coding gene Chr18:79962210-79976489 (-)
C3H/HeJ MGP_C3HHeJ_G0024334
 protein coding gene Chr18:82246251-82260588 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025012
 protein coding gene Chr18:85471648-85485928 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022443
 protein coding gene Chr18:78532151-78546443 (-)
CAST/EiJ MGP_CASTEiJ_G0023807
 protein coding gene Chr18:82545206-82565420 (-)
CBA/J MGP_CBAJ_G0024304
 protein coding gene Chr18:88653689-88667959 (-)
DBA/2J MGP_DBA2J_G0024434
 protein coding gene Chr18:79296169-79310449 (-)
FVB/NJ MGP_FVBNJ_G0024400
 protein coding gene Chr18:78603540-78617892 (-)
LP/J MGP_LPJ_G0024518
 protein coding gene Chr18:83236639-83250956 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024430
 protein coding gene Chr18:89878186-89892441 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025061
 protein coding gene Chr18:82311736-82326024 (-)
PWK/PhJ MGP_PWKPhJ_G0023552
 protein coding gene Chr18:79663777-79683896 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023358
 protein coding gene Chr18:82423841-82438462 (-)
WSB/EiJ MGP_WSBEiJ_G0023869
 protein coding gene Chr18:82291093-82305407 (-)



Homology
more
  • Human Ortholog
    GALR1, galanin receptor 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GALR1, galanin receptor 1
  • Synonyms
    GALNR, GALNR1
  • Links
    NCBI Gene ID: 2587
    neXtProt AC: NX_P47211
    UniProt: P47211

  • Chr Location
    18q23; chr18:77249848-77277900 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 3 alleles in 4 genetic backgrounds
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene does not appear to result in a phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    815
  • Tissues
    55
  • cDNA Data
    8
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14427 NCBI Gene Model | MGI Sequence Detail 14282 C57BL/6J ±  kb
    transcript NM_008082 RefSeq | MGI Sequence Detail 2871 ZRU/MplStud  
    polypeptide P56479 UniProt | EBI | MGI Sequence Detail 348 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      Genomic 2
      cDNA 9
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 72
      Developmental Gene Expression 7
      Gene Ontology 9
      Phenotypes 27
    • Earliest
      J:38577 Simoneaux DK, et al., Galanin receptor gene (Galnr1) is tightly linked to the myelin basic protein gene on Chromosome 18 in mouse. Mamm Genome. 1997;8(Nov):875
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory