About   Help   FAQ
Kif12 Gene Detail
Summary
  • Symbol
    Kif12
  • Name
    kinesin family member 12
  • Synonyms
    N-9 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098232
    NCBI Gene: 16552
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:63083867-63090368 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 33.96 cM, cytoband C1
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    320 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098232
 protein coding gene Chr4:63076185-63090382 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028362
 protein coding gene Chr4:62167412-62173924 (-)
A/J MGP_AJ_G0028323
 protein coding gene Chr4:59921569-59928081 (-)
AKR/J MGP_AKRJ_G0028272
 protein coding gene Chr4:61565771-61572283 (-)
BALB/cJ MGP_BALBcJ_G0028343
 protein coding gene Chr4:60088239-60094751 (-)
C3H/HeJ MGP_C3HHeJ_G0028061
 protein coding gene Chr4:62080426-62086938 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028783
 protein coding gene Chr4:64303270-64309782 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026089
 protein coding gene Chr4:57257963-57264533 (-)
CAST/EiJ MGP_CASTEiJ_G0027497
 protein coding gene Chr4:60047698-60054234 (-)
CBA/J MGP_CBAJ_G0028028
 protein coding gene Chr4:66529769-66536281 (-)
DBA/2J MGP_DBA2J_G0028178
 protein coding gene Chr4:59778009-59784521 (-)
FVB/NJ MGP_FVBNJ_G0028143
 protein coding gene Chr4:59029076-59035588 (-)
LP/J MGP_LPJ_G0028275
 protein coding gene Chr4:62433377-62439889 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028170
 protein coding gene Chr4:69635872-69642384 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028819
 protein coding gene Chr4:61671690-61678202 (-)
PWK/PhJ MGP_PWKPhJ_G0027224
 protein coding gene Chr4:58267847-58274479 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027053
 protein coding gene Chr4:59134309-59140842 (-)
WSB/EiJ MGP_WSBEiJ_G0027577
 protein coding gene Chr4:61671884-61678396 (-)



Homology
more
  • Human Ortholog
    KIF12, kinesin family member 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIF12, kinesin family member 12
  • Synonyms
    PFIC8
  • Links
    NCBI Gene ID: 113220
    neXtProt AC: NX_Q96FN5
    UniProt: Q96FN5

  • Chr Location
    9q32; chr9:114086126-114099292 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human KIF12 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    21
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028357 Ensembl Gene Model | MGI Sequence Detail 6502 C57BL/6J ±  kb
transcript ENSMUST00000156618 Ensembl | MGI Sequence Detail 2258 Not Applicable  
polypeptide ENSMUSP00000152690 Ensembl | MGI Sequence Detail 643 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    Genomic 1
    cDNA 21

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:18490 Winter H, et al., Sequence and expression of murine type I hair keratins mHa2 and mHa3. Exp Cell Res. 1994 Jun;212(2):190-200
  • Latest
    J:306107 Niborski LL, et al., Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory