About   Help   FAQ
Camk1 Gene Detail
Summary
  • Symbol
    Camk1
  • Name
    calcium/calmodulin-dependent protein kinase I
  • Synonyms
    Camk, CaMKIalpha, D6Ertd263e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098535
    NCBI Gene: 52163
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:113311085-113320883 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 52.75 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    309 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098535
 protein coding gene Chr6:113311085-113320945 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031118
 protein coding gene Chr6:115846946-115857810 (-)
A/J MGP_AJ_G0031087
 protein coding gene Chr6:111406938-111417763 (-)
AKR/J MGP_AKRJ_G0031018
 protein coding gene Chr6:114398492-114410105 (-)
BALB/cJ MGP_BALBcJ_G0031098
 protein coding gene Chr6:111356082-111365901 (-)
C3H/HeJ MGP_C3HHeJ_G0030610
 protein coding gene Chr6:69886406-69896001 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031557
 protein coding gene Chr6:118846853-118859242 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028721
 protein coding gene Chr6:108414155-108423959 (-)
CAST/EiJ MGP_CASTEiJ_G0030205
 protein coding gene Chr6:114833489-114843123 (-)
CBA/J MGP_CBAJ_G0030784
 protein coding gene Chr6:123542682-123552274 (-)
DBA/2J MGP_DBA2J_G0030937
 protein coding gene Chr6:110490628-110500249 (-)
FVB/NJ MGP_FVBNJ_G0030891
 protein coding gene Chr6:109489356-109498948 (-)
LP/J MGP_LPJ_G0031017
 protein coding gene Chr6:115887724-115897528 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030925
 protein coding gene Chr6:127805785-127816536 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031584
 protein coding gene Chr6:114414122-114423752 (-)
PWK/PhJ MGP_PWKPhJ_G0029921
 protein coding gene Chr6:109440807-109450829 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029749
 protein coding gene Chr6:113232278-113242089 (-)
WSB/EiJ MGP_WSBEiJ_G0030289
 protein coding gene Chr6:114786493-114796519 (-)



Homology
more
  • Human Ortholog
    CAMK1, calcium/calmodulin dependent protein kinase I
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CAMK1, calcium/calmodulin dependent protein kinase I
  • Synonyms
    CAMKI
  • Links
    NCBI Gene ID: 8536
    neXtProt AC: NX_Q14012
    UniProt: Q14012

  • Chr Location
    3p25.3; chr3:9757347-9769992 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    52
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    966
  • Tissues
    119
  • cDNA Data
    14
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 52163 NCBI Gene Model | MGI Sequence Detail 9799 C57BL/6J ±  kb
    transcript NM_133926 RefSeq | MGI Sequence Detail 1434 ZRU/MplStud  
    polypeptide Q91YS8 UniProt | EBI | MGI Sequence Detail 374 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 15
      Primer pair 5
      Other 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2141437
    References
    more
    • Summaries
      All 62
      Developmental Gene Expression 8
      Gene Ontology 13
      Phenotypes 14
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:346346 Yuan D, et al., IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy. Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):167022
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory