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Coq5 Gene Detail
Summary
  • Symbol
    Coq5
  • Name
    coenzyme Q5 methyltransferase
  • Synonyms
    1810014G04Rik, D5Ertd33e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098643
    NCBI Gene: 52064
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:115417752-115435029 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 56.03 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    550 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098643
 protein coding gene Chr5:115417725-115435031 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029963
 protein coding gene Chr5:118127708-118146407 (+)
A/J MGP_AJ_G0029928
 protein coding gene Chr5:113444834-113462416 (+)
AKR/J MGP_AKRJ_G0029866
 protein coding gene Chr5:117080517-117101497 (+)
BALB/cJ MGP_BALBcJ_G0029939
 protein coding gene Chr5:114841499-114859235 (+)
C3H/HeJ MGP_C3HHeJ_G0029658
 protein coding gene Chr5:117585693-117602796 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030393
 protein coding gene Chr5:122688754-122709291 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027620
 protein coding gene Chr5:108220205-108238731 (+)
CAST/EiJ MGP_CASTEiJ_G0029067
 protein coding gene Chr5:116502190-116519508 (+)
CBA/J MGP_CBAJ_G0029626
 protein coding gene Chr5:127397747-127419877 (+)
DBA/2J MGP_DBA2J_G0029776
 protein coding gene Chr5:113518137-113535832 (+)
FVB/NJ MGP_FVBNJ_G0029732
 protein coding gene Chr5:112335948-112355157 (+)
LP/J MGP_LPJ_G0029864
 protein coding gene Chr5:118704140-118722263 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029763
 protein coding gene Chr5:131721363-131739549 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030434
 protein coding gene Chr5:116541795-116562103 (+)
PWK/PhJ MGP_PWKPhJ_G0028780
 protein coding gene Chr5:112179065-112196265 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028618
 protein coding gene Chr5:114098811-114115448 (+)
WSB/EiJ MGP_WSBEiJ_G0029142
 protein coding gene Chr5:117139546-117159505 (+)



Homology
more
  • Human Ortholog
    COQ5, coenzyme Q5, methyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COQ5, coenzyme Q5, methyltransferase
  • Synonyms
    COQ10D9
  • Links
    NCBI Gene ID: 84274
    neXtProt AC: NX_Q5HYK3
    UniProt: Q5HYK3

  • Chr Location
    12q24.31; chr12:120503279-120534434 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COQ5 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    20
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    13
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Coq5
  • Find Mice (IMSR)
    19 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    3
  • cDNA Data
    49
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52064 NCBI Gene Model | MGI Sequence Detail 17278 C57BL/6J ±  kb
transcript NM_026504 RefSeq | MGI Sequence Detail 2008 ZRU/MplStud  
polypeptide Q9CXI0 UniProt | EBI | MGI Sequence Detail 327 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005754 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
    (term hierarchy)
  • EC
    2.1.1.201
  • InterPro Domains
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
    IPR004033 UbiE/COQ5 methyltransferase
    IPR023576 UbiE/COQ5 methyltransferase, conserved site
  • GlyGen
    Q9CXI0 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 51
    cDNA 49
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1915257
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:305946 Xu M, et al., The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory