About   Help   FAQ
Nrap Gene Detail
Summary
  • Symbol
    Nrap
  • Name
    nebulin-related anchoring protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098765
    NCBI Gene: 18175
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:56308473-56378466 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 51.80 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2475 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098765
 protein coding gene Chr19:56308467-56378469 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025262
 protein coding gene Chr19:56659024-56735086 (-)
A/J MGP_AJ_G0025238
 protein coding gene Chr19:53861808-53932026 (-)
AKR/J MGP_AKRJ_G0025207
 protein coding gene Chr19:55561011-55630740 (-)
BALB/cJ MGP_BALBcJ_G0025233
 protein coding gene Chr19:53949759-54019847 (-)
C3H/HeJ MGP_C3HHeJ_G0024993
 protein coding gene Chr19:55799613-55872359 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025676
 protein coding gene Chr19:58023060-58100879 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023088
 protein coding gene Chr19:52789239-52860552 (-)
CAST/EiJ MGP_CASTEiJ_G0024458
 protein coding gene Chr19:55810399-55888405 (-)
CBA/J MGP_CBAJ_G0024973
 protein coding gene Chr19:60897970-60978032 (-)
DBA/2J MGP_DBA2J_G0025105
 protein coding gene Chr19:53655969-53725890 (-)
FVB/NJ MGP_FVBNJ_G0025066
 protein coding gene Chr19:53359979-53429866 (-)
LP/J MGP_LPJ_G0025191
 protein coding gene Chr19:56521278-56600062 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025099
 protein coding gene Chr19:60205871-60282320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025734
 protein coding gene Chr19:55777023-55847618 (-)
PWK/PhJ MGP_PWKPhJ_G0024206
 protein coding gene Chr19:53603806-53678243 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024009
 protein coding gene Chr19:54449697-54520319 (-)
WSB/EiJ MGP_WSBEiJ_G0024528
 protein coding gene Chr19:55902884-55980672 (-)



Homology
more
  • Human Ortholog
    NRAP, nebulin related anchoring protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NRAP, nebulin related anchoring protein
  • Synonyms
    N-RAP
  • Links
    NCBI Gene ID: 4892
    neXtProt AC: NX_Q86VF7
    UniProt: Q86VF7

  • Chr Location
    10q25.3; chr10:113588714-113664070 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    14
  • cDNA Data
    10
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 18175 NCBI Gene Model | MGI Sequence Detail 69994 C57BL/6J ±  kb
transcript NM_001403176 RefSeq | MGI Sequence Detail 5501 ZRU/MplStud  
polypeptide Q80XB4 UniProt | EBI | MGI Sequence Detail 1728 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 10
    Primer pair 4

    Microarray probesets 3
References
more
  • Summaries
    All 42
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:42072 Luo G, et al., Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes. Genomics. 1997 Oct 1;45(1):229-32
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory