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Idh3g Gene Detail
Summary
  • Symbol
    Idh3g
  • Name
    isocitrate dehydrogenase 3 (NAD+), gamma
  • Feature Type
    protein coding gene
  • IDs
    MGI:1099463
    NCBI Gene: 15929
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:72822569-72830471 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 37.41 cM, cytoband A7.3-B
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1099463
 protein coding gene ChrX:72822569-72830503 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035820
 protein coding gene ChrX:69554253-69562187 (-)
A/J MGP_AJ_G0035801
 protein coding gene ChrX:69751224-69759158 (-)
AKR/J MGP_AKRJ_G0035726
 protein coding gene ChrX:71571861-71579795 (-)
BALB/cJ MGP_BALBcJ_G0035786
 protein coding gene ChrX:68782573-68790507 (-)
C3H/HeJ MGP_C3HHeJ_G0035491
 protein coding gene ChrX:70027816-70035750 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036316
 protein coding gene ChrX:71684801-71692735 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033160
 protein coding gene ChrX:68781791-68789802 (-)
CAST/EiJ MGP_CASTEiJ_G0034782
 protein coding gene ChrX:55373822-55381754 (-)
CBA/J MGP_CBAJ_G0035466
 protein coding gene ChrX:73663751-73671685 (-)
DBA/2J MGP_DBA2J_G0035623
 protein coding gene ChrX:69209365-69217299 (-)
FVB/NJ MGP_FVBNJ_G0035567
 protein coding gene ChrX:68540430-68548368 (-)
LP/J MGP_LPJ_G0035708
 protein coding gene ChrX:70336828-70344762 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035605
 protein coding gene ChrX:76233337-76241271 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036338
 protein coding gene ChrX:69375602-69383540 (-)
PWK/PhJ MGP_PWKPhJ_G0034481
 protein coding gene ChrX:53389687-53397607 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034315
 protein coding gene ChrX:56277061-56285020 (-)
WSB/EiJ MGP_WSBEiJ_G0034923
 protein coding gene ChrX:68649462-68657412 (-)



Homology
more
  • Human Ortholog
    IDH3G, isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IDH3G, isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
  • Synonyms
    H-IDHG
  • Links
    NCBI Gene ID: 3421
    neXtProt AC: NX_P51553
    UniProt: P51553

  • Chr Location
    Xq28; chrX:153785766-153794512 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    830
  • Tissues
    100
  • cDNA Data
    300
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 15929 NCBI Gene Model | MGI Sequence Detail 7903 C57BL/6J ±  kb
    transcript NM_008323 RefSeq | MGI Sequence Detail 1299 ZRU/MplStud  
    polypeptide P70404 UniProt | EBI | MGI Sequence Detail 393 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000008891 isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
      (term hierarchy)
    • InterPro Domains
      IPR004434 Isocitrate dehydrogenase NAD-dependent
      IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site
      IPR024084 Isopropylmalate dehydrogenase-like domain
    • GlyGen
      P70404 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 303
      Genomic 1
      cDNA 300
      Primer pair 2

      Microarray probesets 5
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 6
      Gene Ontology 10
      Phenotypes 10
    • Earliest
      J:42590 Brenner V, et al., Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse. Genomics. 1997 Aug 15;44(1):8-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory