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Fpr3 Gene Detail
Summary
  • Symbol
    Fpr3
  • Name
    formyl peptide receptor 3
  • Synonyms
    Fprl1, Fpr-rs1, LXA4-R, Lxa4r
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194495
    NCBI Gene: 14294
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr17:18190720-18191939 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 10.66 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194495
 protein coding gene Chr17:18108114-18191939 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023188
 protein coding gene Chr17:15894047-16003888 (+)
A/J MGP_AJ_G0023152
 protein coding gene Chr17:15539462-15625481 (+)
AKR/J MGP_AKRJ_G0023123
 protein coding gene Chr17:15614784-15693504 (+)
BALB/cJ MGP_BALBcJ_G0023153
 protein coding gene Chr17:15485709-15574498 (+)
C3H/HeJ MGP_C3HHeJ_G0022913
 protein coding gene Chr17:15844016-15952035 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023596
 protein coding gene Chr17:16682949-16802583 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021108
 protein coding gene Chr17:13387199-13441566 (+)
CAST/EiJ MGP_CASTEiJ_G0022432
 protein coding gene Chr17:15650081-15745091 (+)
CBA/J MGP_CBAJ_G0022890
 protein coding gene Chr17:17253320-17345217 (+)
DBA/2J MGP_DBA2J_G0023023
 protein coding gene Chr17:15253658-15337689 (+)
FVB/NJ MGP_FVBNJ_G0022991
 protein coding gene Chr17:15067930-15154495 (+)
LP/J MGP_LPJ_G0023097
 protein coding gene Chr17:15887971-15969644 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023012
 protein coding gene Chr17:16854801-16944776 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023633
 protein coding gene Chr17:15808250-15885412 (+)
PWK/PhJ MGP_PWKPhJ_G0022180
 protein coding gene Chr17:14887046-14972066 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022009
 protein coding gene Chr17:14896719-14952781 (+)
WSB/EiJ MGP_WSBEiJ_G0022491
 protein coding gene Chr17:16090443-16186138 (+)



Homology
more
  • Human Ortholog
    FPR2, formyl peptide receptor 2
  • Vertebrate Orthologs
    11
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FPR2, formyl peptide receptor 2
  • Synonyms
    ALX, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
  • Links
    NCBI Gene ID: 2358
    neXtProt AC: NX_P25090
    UniProt: P25090

  • Chr Location
    19q13.41; chr19:51752026-51770531 (+)  GRCh38
  • Human Ortholog
    FPR3, formyl peptide receptor 3
  • Synonyms
    FML2_HUMAN, FMLP-R-II, FMLPY, FPRH1, FPRH2, FPRL2, RMLP-R-I
  • Links
    NCBI Gene ID: 2359
    neXtProt AC: NX_P25089
    UniProt: P25089

  • Chr Location
    19q13.41; chr19:51795157-51826190 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14294 NCBI Gene Model | MGI Sequence Detail 1220 C57BL/6J ±  kb
    transcript NM_008042 RefSeq | MGI Sequence Detail 1220 Not Specified  
    polypeptide O08790 UniProt | EBI | MGI Sequence Detail 351 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR000826 Formyl peptide receptor-related
      IPR017452 GPCR, rhodopsin-like, 7TM
      IPR000276 G protein-coupled receptor, rhodopsin-like
    • GlyGen
      O08790 2 sites
    Molecular
    Reagents
    less
    • All nucleic 11
      Genomic 8
      cDNA 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1278320
    References
    more
    • Summaries
      All 44
      Gene Ontology 7
      Phenotypes 9
    • Earliest
      J:40139 Takano T, et al., Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. J Exp Med. 1997 May 5;185(9):1693-704
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory