Igf2os Gene Detail

Summary

• Symbol
  Igf2os
• Name
  insulin-like growth factor 2, opposite strand
• Synonyms
  Igf2as, Peg8

• Feature Type
  antisense lncRNA gene
  BioType Conflict
  
• IDs
  MGI:1195257
  NCBI Gene: 111975
• Alliance
  gene page
• Transcription Start Sites
  18 TSS

Location &
Maps

• Sequence Map
  Chr7:142213430-142224093 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 87.99 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  184 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1195257	antisense lncRNA gene	Chr7:142213417-142224093 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0004522	antisense lncRNA gene	Chr7:147926973-147938745 (+)
A/J	MGP_AJ_G0004502	antisense lncRNA gene	Chr7:143654819-143666212 (+)
AKR/J	MGP_AKRJ_G0004485	antisense lncRNA gene	Chr7:147684475-147706002 (+)
BALB/cJ	MGP_BALBcJ_G0004487	antisense lncRNA gene	Chr7:143426309-143438366 (+)
C3H/HeJ	MGP_C3HHeJ_G0004436	antisense lncRNA gene	Chr7:147447234-147459400 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0004637	antisense lncRNA gene	Chr7:153275508-153287829 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0004091	antisense lncRNA gene	Chr7:144863317-144874033 (+)
CAST/EiJ	MGP_CASTEiJ_G0004396	antisense lncRNA gene	Chr7:139768512-139779251 (+)
CBA/J	MGP_CBAJ_G0004431	antisense lncRNA gene	Chr7:158523837-158536614 (+)
DBA/2J	MGP_DBA2J_G0004445	antisense lncRNA gene	Chr7:141606275-141617386 (+)
FVB/NJ	MGP_FVBNJ_G0004462	antisense lncRNA gene	Chr7:141543742-141554448 (+)
LP/J	MGP_LPJ_G0004526	antisense lncRNA gene	Chr7:149435348-149447097 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0004451	antisense lncRNA gene	Chr7:159136899-159148868 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0004636	antisense lncRNA gene	Chr7:146642028-146656189 (+)
PWK/PhJ	MGP_PWKPhJ_G0004349	antisense lncRNA gene	Chr7:134935774-134946968 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0004290	antisense lncRNA gene	Chr7:133434461-133447906 (+)
WSB/EiJ	MGP_WSBEiJ_G0004435	antisense lncRNA gene	Chr7:147632081-147642565 (+)

Homology

• Human Ortholog
  IGF2-AS, IGF2 antisense RNA

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IGF2-AS, IGF2 antisense RNA
  
• Synonyms
  IGF2AS, IGF2-AS1, PEG8
• Links
  HGNC:14062

  NCBI Gene ID: 51214

  
  
• Chr Location
  11p15.5; chr11:2140501-2148666 (+)  GRCh38

---

• MGI Vertebrate Homology
  Igf2os stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: IGF2-AS
• Gene Tree
  Igf2os
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  762
• Tissues
  15
• cDNA Data
  8
• Literature Summary
  5

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  32
• RefSeq
  1
• UniProt
  2

• Ensembl
  ENSMUSG00000086266 (Evidence)
• NCBI Gene
  111975

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000086266	Ensembl Gene Model | MGI Sequence Detail	10664	C57BL/6J
transcript	ENSMUST00000141681	Ensembl | MGI Sequence Detail	4778	Not Applicable
polypeptide	A0A159ZPB9	UniProt | EBI | MGI Sequence Detail	149	Not Applicable

Protein
Information

• UniProt
  2 Sequences

Molecular
Reagents

• All nucleic 13

  Genomic 5

  cDNA 8

  
  

  Microarray probesets 3

References

• Summaries
  All 19

  Developmental Gene Expression 5

  Gene Ontology 1

  Phenotypes 1
• Earliest
  J:14435 Rivkin M, et al., Identification of an antisense transcript from the IGF-II locus in mouse. Mol Reprod Dev. 1993 Aug;35(4):394-7
• Latest
  J:210271 Duart-Garcia C, et al., Functional expression study of igf2 antisense transcript in mouse. Int J Genomics. 2014;2014:390296

TSS for Igf2os:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr70241	Chr7:142212269-142212322 (+)	-1,134 bp
Tssr70242	Chr7:142212333-142212366 (+)	-1,080 bp
Tssr70243	Chr7:142212597-142212636 (+)	-813 bp
Tssr70244	Chr7:142212647-142212690 (+)	-761 bp
Tssr70245	Chr7:142212758-142212769 (+)	-666 bp
Tssr70246	Chr7:142212840-142212852 (+)	-584 bp
Tssr70247	Chr7:142212886-142212915 (+)	-529 bp
Tssr70248	Chr7:142212961-142212989 (+)	-455 bp
Tssr70249	Chr7:142214071-142214080 (+)	646 bp
Tssr70250	Chr7:142214191-142214196 (+)	764 bp
Tssr70251	Chr7:142214217-142214234 (+)	796 bp
Tssr70252	Chr7:142214314-142214321 (+)	888 bp
Tssr70253	Chr7:142214360-142214385 (+)	943 bp
Tssr70254	Chr7:142214391-142214404 (+)	968 bp
Tssr70255	Chr7:142214468-142214497 (+)	1,053 bp
Tssr70256	Chr7:142218866-142218894 (+)	5,450 bp
Tssr70257	Chr7:142219522-142219531 (+)	6,097 bp
Tssr70258	Chr7:142219540-142219557 (+)	6,119 bp