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Zmat3 Gene Detail
Summary
  • Symbol
    Zmat3
  • Name
    zinc finger matrin type 3
  • Synonyms
    Wig1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1195270
    NCBI Gene: 22401
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:32388941-32419814 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 15.67 cM, cytoband B
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1073 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1195270
 protein coding gene Chr3:32388941-32420163 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027135
 protein coding gene Chr3:29925700-29958961 (-)
A/J MGP_AJ_G0027095
 protein coding gene Chr3:29519250-29552198 (-)
AKR/J MGP_AKRJ_G0027064
 protein coding gene Chr3:29980335-30015392 (-)
BALB/cJ MGP_BALBcJ_G0027107
 protein coding gene Chr3:29170362-29201523 (-)
C3H/HeJ MGP_C3HHeJ_G0026850
 protein coding gene Chr3:29996590-30029898 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027553
 protein coding gene Chr3:31435049-31467593 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024914
 protein coding gene Chr3:27348725-27379992 (-)
CAST/EiJ MGP_CASTEiJ_G0026303
 protein coding gene Chr3:29850168-29887875 (-)
CBA/J MGP_CBAJ_G0026827
 protein coding gene Chr3:32264383-32303842 (-)
DBA/2J MGP_DBA2J_G0026961
 protein coding gene Chr3:28986408-29019179 (-)
FVB/NJ MGP_FVBNJ_G0026929
 protein coding gene Chr3:28457421-28490926 (-)
LP/J MGP_LPJ_G0027073
 protein coding gene Chr3:30703184-30735722 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026949
 protein coding gene Chr3:34789162-34821735 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027612
 protein coding gene Chr3:29752765-29795298 (-)
PWK/PhJ MGP_PWKPhJ_G0026036
 protein coding gene Chr3:28525937-28557732 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025848
 protein coding gene Chr3:29163848-29196743 (-)
WSB/EiJ MGP_WSBEiJ_G0026377
 protein coding gene Chr3:29773794-29808275 (-)



Homology
more
  • Human Ortholog
    ZMAT3, zinc finger matrin-type 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZMAT3, zinc finger matrin-type 3
  • Synonyms
    PAG608, WIG-1, WIG1
  • Links
    NCBI Gene ID: 64393
    neXtProt AC: NX_Q9HA38
    UniProt: Q9HA38

  • Chr Location
    3q26.32; chr3:178960121-179072513 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Homozygous knockout does not affect lymphoid cell proliferation or apoptosis, nor mouse embryo fibroblast senescence.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    28
  • cDNA Data
    75
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22401 NCBI Gene Model | MGI Sequence Detail 30874 C57BL/6J ±  kb
transcript NM_009517 RefSeq | MGI Sequence Detail 7784 C57BL/6  
polypeptide O54836 UniProt | EBI | MGI Sequence Detail 290 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 82
    cDNA 77
    Primer pair 5

    Microarray probesets 3
References
more
  • Summaries
    All 52
    Developmental Gene Expression 10
    Diseases 1
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:44645 Varmeh-Ziaie S, et al., Wig-1, a new p53-induced gene encoding a zinc finger protein. Oncogene. 1997 Nov 27;15(22):2699-704
  • Latest
    J:345063 Brennan MS, et al., Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice. Cell Death Differ. 2024 Feb;31(2):159-169
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory