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Dlx1as Gene Detail
Summary
  • Symbol
    Dlx1as
  • Name
    distal-less homeobox 1, antisense
  • Synonyms
    Dlx1as, Dlx1os
Location &
Maps
more
  • Sequence Map
    Chr2:71360982-71368235 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 42.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1195983
 antisense lncRNA gene Chr2:71346798-71368252 (-)
129S1/SvImJ MGP_129S1SvImJ_G0003582
 antisense lncRNA gene Chr2:71634755-71657328 (-)
A/J MGP_AJ_G0003564
 antisense lncRNA gene Chr2:68829592-68850919 (-)
AKR/J MGP_AKRJ_G0003542
 antisense lncRNA gene Chr2:70719823-70741307 (-)
BALB/cJ MGP_BALBcJ_G0003553
 antisense lncRNA gene Chr2:69018238-69039995 (-)
C3H/HeJ MGP_C3HHeJ_G0003500
 antisense lncRNA gene Chr2:70926033-70948101 (-)
C57BL/6NJ MGP_C57BL6NJ_G0003691
 antisense lncRNA gene Chr2:73795409-73816714 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0003200
 antisense lncRNA gene Chr2:66053638-66075174 (-)
CAST/EiJ MGP_CASTEiJ_G0003463
 antisense lncRNA gene Chr2:71115455-71137794 (-)
CBA/J MGP_CBAJ_G0003497
 antisense lncRNA gene Chr2:76514492-76538261 (-)
DBA/2J MGP_DBA2J_G0003505
 antisense lncRNA gene Chr2:68468645-68489937 (-)
FVB/NJ MGP_FVBNJ_G0003525
 antisense lncRNA gene Chr2:67857757-67879405 (-)
LP/J MGP_LPJ_G0003578
 antisense lncRNA gene Chr2:71494144-71515377 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0003513
 antisense lncRNA gene Chr2:78501335-78522824 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0003693
 antisense lncRNA gene Chr2:70823855-70846266 (-)
PWK/PhJ MGP_PWKPhJ_G0003418
 antisense lncRNA gene Chr2:68340101-68362092 (-)
SPRET/EiJ MGP_SPRETEiJ_G0003362
 antisense lncRNA gene Chr2:71011114-71033015 (-)
WSB/EiJ MGP_WSBEiJ_G0003498
 antisense lncRNA gene Chr2:71257190-71280512 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    40 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit dysmorphic alicochlear commissure.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    11
  • cDNA Data
    6
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      31
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 111970 NCBI Gene Model | MGI Sequence Detail 7254 C57BL/6J ±  kb
    transcript NR_002854 RefSeq | MGI Sequence Detail 2793 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 7
      Primer pair 6

      Microarray probesets 3
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 8
      Gene Ontology 1
      Phenotypes 40
    • Earliest
      J:34614 McGuinness T, et al., Sequence, organization, and transcription of the Dlx-1 and Dlx-2 locus. Genomics. 1996 Aug 1;35(3):473-85
    • Latest
      J:321980 Su Z, et al., Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory