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Trav5-4 Gene Detail
Summary
  • Symbol
    Trav5-4
  • Name
    T cell receptor alpha variable 5-4
  • Feature Type
    gene segment
  • IDs
    MGI:1196221
    NCBI Gene: 21507
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr14:53941464-53941971 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 27.48 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    170 from dbSNP Build 142
  • Strain Annotations
    10
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196221
gene segment Chr14:53941464-53941971 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0002506
gene segment Chr14:45864451-45864959 (+)
AKR/J MGP_AKRJ_G0002495
gene segment Chr14:47501980-47502488 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0002476
gene segment Chr14:47282497-47283004 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0002469
gene segment Chr14:44334327-44334831 (+)
CBA/J MGP_CBAJ_G0002467
gene segment Chr14:50657612-50658119 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0002534
gene segment Chr14:47740349-47740856 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002463
gene segment Chr14:50125026-50125533 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002636
gene segment Chr14:46828664-46829172 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0002379
gene segment Chr14:43356734-43357240 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TRAV13-1, T cell receptor alpha variable 13-1
  • Vertebrate Orthologs
    12
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRAV13-1, T cell receptor alpha variable 13-1
  • Synonyms
    TCRAV13S1, TCRAV8S1, TRAV131
  • Links
    NCBI Gene ID: 28671
    UniProt: A0A0B4J241

  • Chr Location
    14q11.2; chr14:21868839-21869365 (+)  GRCh38

  • Human Ortholog
    TRAV13-2, T cell receptor alpha variable 13-2
  • Synonyms
    TCRAV13S2, TCRAV8S2, TRAV132
  • Links
    NCBI Gene ID: 28670
    UniProt: A0A0B4J235

  • Chr Location
    14q11.2; chr14:21918188-21918756 (+)  GRCh38

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 21507 NCBI Gene Model | MGI Sequence Detail 508 C57BL/6J ±  kb
transcript U07877 GenBank | ENA | DDBJ | MGI Sequence Detail 372 (SWR x NZB)F1  
polypeptide A0A075B652 UniProt | EBI | MGI Sequence Detail 114 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
    IPR051006 T cell receptor variable domain
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Other 1
References
more
  • Summaries
    All 13
    Gene Ontology 1
  • Earliest
    J:8208 Epstein R, et al., The cytotoxic T cell response to the male-specific histocompatibility antigen (H-Y) is controlled by two dominant immune response genes, one in the MHC, the other in the Tar alpha-locus. J Exp Med. 1986 Apr 1;163(4):759-73
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory