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Tspan14 Gene Detail
Summary
  • Symbol
    Tspan14
  • Name
    tetraspanin 14
  • Synonyms
    D14Ertd226e, Tm4sf14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196325
    NCBI Gene: 52588
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:40628402-40688764 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 22.36 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1491 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196325
 protein coding gene Chr14:40628384-40688835 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021192
 protein coding gene Chr14:34529471-34599823 (-)
A/J MGP_AJ_G0021140
 protein coding gene Chr14:33190758-33251689 (-)
AKR/J MGP_AKRJ_G0021117
 protein coding gene Chr14:34550817-34611478 (-)
BALB/cJ MGP_BALBcJ_G0021144
 protein coding gene Chr14:33409276-33469643 (-)
C3H/HeJ MGP_C3HHeJ_G0020927
 protein coding gene Chr14:34506064-34570128 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021576
 protein coding gene Chr14:35924403-35990705 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019138
 protein coding gene Chr14:32823748-32882795 (-)
CAST/EiJ MGP_CASTEiJ_G0020452
 protein coding gene Chr14:34283143-34343800 (-)
CBA/J MGP_CBAJ_G0020893
 protein coding gene Chr14:37143811-37207197 (-)
DBA/2J MGP_DBA2J_G0021016
 protein coding gene Chr14:33143940-33208948 (-)
FVB/NJ MGP_FVBNJ_G0021000
 protein coding gene Chr14:33086906-33147722 (-)
LP/J MGP_LPJ_G0021085
 protein coding gene Chr14:34755055-34823202 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021026
 protein coding gene Chr14:36782963-36846884 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021609
 protein coding gene Chr14:34336898-34398444 (-)
PWK/PhJ MGP_PWKPhJ_G0020200
 protein coding gene Chr14:32624537-32686052 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020024
 protein coding gene Chr14:33956791-34018469 (-)
WSB/EiJ MGP_WSBEiJ_G0020507
 protein coding gene Chr14:34443956-34505753 (-)



Homology
more
  • Human Ortholog
    TSPAN14, tetraspanin 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSPAN14, tetraspanin 14
  • Synonyms
    DC-TM4F2, TM4SF14, tspan-14
  • Links
    NCBI Gene ID: 81619
    neXtProt AC: NX_Q8NG11
    UniProt: Q8NG11

  • Chr Location
    10q23.1; chr10:80454265-80533124 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    87 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    760
  • Tissues
    39
  • cDNA Data
    11
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037824 Ensembl Gene Model | MGI Sequence Detail 60363 C57BL/6J ±  kb
transcript ENSMUST00000047652 Ensembl | MGI Sequence Detail 2475 Not Applicable  
polypeptide ENSMUSP00000035263 Ensembl | MGI Sequence Detail 270 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 12
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145582
References
more
  • Summaries
    All 116
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 87
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:359444 Jiang H, et al., Divergent sensory pathways of sneezing and coughing. Cell. 2024 Oct 17;187(21):5981-5997.e14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory