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Rdh16 Gene Detail
Summary
  • Symbol
    Rdh16
  • Name
    retinol dehydrogenase 16
  • Synonyms
    cis-retinol/androgen dehydrogenase 1, CRAD1, Rdh6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1201375
    NCBI Gene: 19683
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:127636959-127651715 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 75.70 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    515 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1201375
 protein coding gene Chr10:127636959-127682434 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017838
 protein coding gene Chr10:131429328-131491456 (+)
A/J MGP_AJ_G0017812
 protein coding gene Chr10:126180895-126244274 (+)
AKR/J MGP_AKRJ_G0017776
 protein coding gene Chr10:129901320-129955544 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0017600
 protein coding gene Chr10:130047427-130096956 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018232
 protein coding gene Chr10:135884536-135942988 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015910
 protein coding gene Chr10:120130304-120200849 (+)
CAST/EiJ MGP_CASTEiJ_G0017161
 protein coding gene Chr10:130749176-130787703 (+)
CBA/J MGP_CBAJ_G0017570
 protein coding gene Chr10:141344991-141473355 (+)
DBA/2J MGP_DBA2J_G0017676
 protein coding gene Chr10:125223984-125319178 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0017749
 protein coding gene Chr10:132007102-132112871 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017699
 protein coding gene Chr10:144058479-144096936 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018272
 protein coding gene Chr10:129979966-130042716 (+)
PWK/PhJ MGP_PWKPhJ_G0016944
 protein coding gene Chr10:125440181-125542525 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0017220
 protein coding gene Chr10:130211411-130231659 (+)



Homology
more
  • Human Ortholog
    RDH16, retinol dehydrogenase 16
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RDH16, retinol dehydrogenase 16
  • Synonyms
    hRDH-E, RODH-4, RODH4, SDR9C8
  • Links
    NCBI Gene ID: 8608
    neXtProt AC: NX_O75452
    UniProt: O75452

  • Chr Location
    12q13.3; chr12:56951431-56959374 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    808
  • Tissues
    100
  • cDNA Data
    31
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19683 NCBI Gene Model | MGI Sequence Detail 14757 C57BL/6J ±  kb
    transcript NM_009040 RefSeq | MGI Sequence Detail 3208 C57BL/6  
    polypeptide O54909 UniProt | EBI | MGI Sequence Detail 317 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      Genomic 5
      cDNA 32
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 5
      Gene Ontology 9
      Phenotypes 7
    • Earliest
      J:44862 Chai X, et al., cDNA cloning and characterization of a cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase. J Biol Chem. 1997 Dec 26;272(52):33125-31
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory