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Atp6v0d1 Gene Detail
Summary
  • Symbol
    Atp6v0d1
  • Name
    ATPase, H+ transporting, lysosomal V0 subunit D1
  • Synonyms
    Ac39, Atp6d, lysosomal 38kDa, P39, Vma6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1201778
    NCBI Gene: 11972
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:106251097-106292679 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    906 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1201778
 protein coding gene Chr8:106251093-106292696 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034049
 protein coding gene Chr8:107811848-107858186 (-)
A/J MGP_AJ_G0034030
 protein coding gene Chr8:103504855-103548049 (-)
AKR/J MGP_AKRJ_G0033956
 protein coding gene Chr8:106497751-106541904 (-)
BALB/cJ MGP_BALBcJ_G0034023
 protein coding gene Chr8:103688940-103736961 (-)
C3H/HeJ MGP_C3HHeJ_G0033735
 protein coding gene Chr8:107242447-107286132 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034543
 protein coding gene Chr8:111761248-111818459 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031485
 protein coding gene Chr8:96649135-96691186 (-)
CAST/EiJ MGP_CASTEiJ_G0033061
 protein coding gene Chr8:106740749-106787217 (-)
CBA/J MGP_CBAJ_G0033708
 protein coding gene Chr8:115372365-115425060 (-)
DBA/2J MGP_DBA2J_G0033863
 protein coding gene Chr8:102849401-102893994 (-)
FVB/NJ MGP_FVBNJ_G0033809
 protein coding gene Chr8:101779526-101821892 (-)
LP/J MGP_LPJ_G0033954
 protein coding gene Chr8:108017120-108061272 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033852
 protein coding gene Chr8:118572759-118615848 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034561
 protein coding gene Chr8:106469071-106511140 (-)
PWK/PhJ MGP_PWKPhJ_G0032762
 protein coding gene Chr8:102241096-102285086 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032603
 protein coding gene Chr8:105144413-105188763 (-)
WSB/EiJ MGP_WSBEiJ_G0033177
 protein coding gene Chr8:107127176-107173411 (-)



Homology
more
  • Human Ortholog
    ATP6V0D1, ATPase H+ transporting V0 subunit d1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP6V0D1, ATPase H+ transporting V0 subunit d1
  • Synonyms
    ATP6D, ATP6DV, P39, VATX, VMA6, VPATPD
  • Links
    NCBI Gene ID: 9114
    neXtProt AC: NX_P61421
    UniProt: P61421

  • Chr Location
    16q22.1; chr16:67438014-67481181 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with Atp6v0d1 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    38 phenotypes from 2 alleles in 2 genetic backgrounds
    214 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    914
  • Tissues
    151
  • cDNA Data
    138
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000013160 Ensembl Gene Model | MGI Sequence Detail 41583 C57BL/6J ±  kb
    transcript ENSMUST00000013304 Ensembl | MGI Sequence Detail 1629 Not Applicable  
    polypeptide ENSMUSP00000013304 Ensembl | MGI Sequence Detail 351 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 141
      cDNA 138
      Primer pair 3

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2142492
    References
    more
    • Summaries
      All 255
      Developmental Gene Expression 7
      Diseases 1
      Gene Ontology 11
      Phenotypes 214
    • Earliest
      J:46747 Carrion-Vazquez M, et al., Brain Ac39/physophilin: cloning, coexpression and colocalization with synaptophysin. Eur J Neurosci. 1998 Mar;10(3):1153-66
    • Latest
      J:353959 Aitken TJ, et al., Negative feedback control of hypothalamic feeding circuits by the taste of food. Neuron. 2024 Aug 13;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory