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Cacng1 Gene Detail
Summary
  • Symbol
    Cacng1
  • Name
    calcium channel, voltage-dependent, gamma subunit 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1206582
    NCBI Gene: 12299
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:107594044-107607302 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 70.29 cM, cytoband E1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    548 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1206582
 protein coding gene Chr11:107594044-107607348 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019322
 protein coding gene Chr11:111123797-111137072 (-)
A/J MGP_AJ_G0019290
 protein coding gene Chr11:106355263-106368548 (-)
AKR/J MGP_AKRJ_G0019259
 protein coding gene Chr11:109534728-109548021 (-)
BALB/cJ MGP_BALBcJ_G0019264
 protein coding gene Chr11:106775886-106789181 (-)
C3H/HeJ MGP_C3HHeJ_G0019073
 protein coding gene Chr11:109848916-109862201 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019714
 protein coding gene Chr11:114553714-114567098 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017338
 protein coding gene Chr11:103617166-103630413 (-)
CAST/EiJ MGP_CASTEiJ_G0018626
 protein coding gene Chr11:110947927-110962477 (-)
CBA/J MGP_CBAJ_G0019042
 protein coding gene Chr11:119284664-119300696 (-)
DBA/2J MGP_DBA2J_G0019154
 protein coding gene Chr11:105832810-105846346 (-)
FVB/NJ MGP_FVBNJ_G0019145
 protein coding gene Chr11:105340184-105353449 (-)
LP/J MGP_LPJ_G0019224
 protein coding gene Chr11:111568306-111581584 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019175
 protein coding gene Chr11:118501902-118515183 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019751
 protein coding gene Chr11:110087329-110100742 (-)
PWK/PhJ MGP_PWKPhJ_G0018391
 protein coding gene Chr11:106978673-106992321 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018182
 protein coding gene Chr11:109850905-109865968 (-)
WSB/EiJ MGP_WSBEiJ_G0018677
 protein coding gene Chr11:110035572-110048911 (-)



Homology
more
  • Human Ortholog
    CACNG1, calcium voltage-gated channel auxiliary subunit gamma 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CACNG1, calcium voltage-gated channel auxiliary subunit gamma 1
  • Synonyms
    CACNLG
  • Links
    NCBI Gene ID: 786
    neXtProt AC: NX_Q06432
    UniProt: Q06432

  • Chr Location
    17q24.2; chr17:67044554-67056797 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CACNG1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for null mutations display abnormal muscle calcium currents.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    29
  • cDNA Data
    26
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 12299 NCBI Gene Model | MGI Sequence Detail 13259 C57BL/6J ±  kb
transcript NM_007582 RefSeq | MGI Sequence Detail 1225 Not Specified  
polypeptide O70578 UniProt | EBI | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004950 voltage-dependent calcium channel gamma-1 subunit
    (term hierarchy)
  • InterPro Domains
    IPR004031 PMP-22/EMP/MP20/Claudin
    IPR005421 Voltage-dependent calcium channel, gamma-1 subunit
    IPR008368 Voltage-dependent calcium channel, gamma subunit
  • GlyGen
    O70578 2 sites
Molecular
Reagents
less
  • All nucleic 28
    Genomic 1
    cDNA 26
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:46501 Wissenbach U, et al., The structure of the murine calcium channel gamma-subunit gene and protein. Biol Chem. 1998 Jan;379(1):45-50
  • Latest
    J:263025 Zoupa M, et al., Gene expression profiling in the developing secondary palate in the absence of Tbx1 function. BMC Genomics. 2018 Jun 4;19(1):429
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory