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Palm Gene Detail
Summary
  • Symbol
    Palm
  • Name
    paralemmin
  • Synonyms
    mKIAA0270
  • Feature Type
    protein coding gene
  • IDs
    MGI:1261814
    NCBI Gene: 18483
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79629406-79656730 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    667 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1261814
protein coding gene Chr10:79629406-79656749 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017461
protein coding gene Chr10:80338961-80371306 (+)
A/J MGP_AJ_G0017439
protein coding gene Chr10:77546618-77574963 (+)
AKR/J MGP_AKRJ_G0017400
protein coding gene Chr10:79654203-79683985 (+)
BALB/cJ MGP_BALBcJ_G0017401
protein coding gene Chr10:77773528-77801410 (+)
C3H/HeJ MGP_C3HHeJ_G0017224
protein coding gene Chr10:79763486-79790814 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017855
protein coding gene Chr10:83112478-83143371 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015543
protein coding gene Chr10:73773548-73801659 (+)
CAST/EiJ MGP_CASTEiJ_G0016791
protein coding gene Chr10:79943538-79974778 (+)
CBA/J MGP_CBAJ_G0017196
protein coding gene Chr10:86337382-86367102 (+)
DBA/2J MGP_DBA2J_G0017302
protein coding gene Chr10:76762022-76789611 (+)
FVB/NJ MGP_FVBNJ_G0017296
protein coding gene Chr10:75935593-75968043 (+)
LP/J MGP_LPJ_G0017373
protein coding gene Chr10:80822334-80850917 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017322
protein coding gene Chr10:88318581-88347419 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017896
protein coding gene Chr10:79635037-79669852 (+)
PWK/PhJ MGP_PWKPhJ_G0016572
protein coding gene Chr10:76622088-76649756 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016361
protein coding gene Chr10:78613892-78641528 (+)
WSB/EiJ MGP_WSBEiJ_G0016851
protein coding gene Chr10:79663733-79692657 (+)



Homology
more
  • Human Ortholog
    PALM, paralemmin
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PALM, paralemmin
  • Synonyms
    PALM1
  • Links
    NCBI Gene ID: 5064
    neXtProt AC: NX_O75781
    UniProt: O75781

  • Chr Location
    19p13.3; chr19:708935-748329 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable, healthy, fertile and overtly normal, and show normal development and physiological function of the lymphatic system.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035863 Ensembl Gene Model | MGI Sequence Detail 27325 C57BL/6J ±  kb
    transcript ENSMUST00000046945 Ensembl | MGI Sequence Detail 2651 Not Applicable  
    polypeptide ENSMUSP00000040596 Ensembl | MGI Sequence Detail 383 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 104
      cDNA 103
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 15
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory