About   Help   FAQ
Mrpl48 Gene Detail
Summary
  • Symbol
    Mrpl48
  • Name
    mitochondrial ribosomal protein L48
  • Synonyms
    1810030E20Rik, CGI-118, D4Ertd786e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289321
    NCBI Gene: 52443
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:100194986-100257508 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.36 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1330 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289321
 protein coding gene Chr7:100194958-100257508 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032573
 protein coding gene Chr7:103438537-103499919 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0032483
 protein coding gene Chr7:103231493-103292680 (-)
BALB/cJ MGP_BALBcJ_G0032558
 protein coding gene Chr7:100513259-100576238 (-)
C3H/HeJ MGP_C3HHeJ_G0032273
 protein coding gene Chr7:103607366-103674832 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033056
 protein coding gene Chr7:107365706-107425559 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030050
 protein coding gene Chr7:103230922-103289818 (-)
CAST/EiJ MGP_CASTEiJ_G0031600
 protein coding gene Chr7:95160498-95229708 (-)
CBA/J MGP_CBAJ_G0032240
 protein coding gene Chr7:111049805-111128122 (-)
DBA/2J MGP_DBA2J_G0032391
 protein coding gene Chr7:99161961-99227807 (-)
FVB/NJ MGP_FVBNJ_G0032348
 protein coding gene Chr7:98946771-99006501 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0032381
 protein coding gene Chr7:112472011-112535751 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033078
 protein coding gene Chr7:102498957-102559598 (-)
PWK/PhJ MGP_PWKPhJ_G0031318
 protein coding gene Chr7:92278224-92346056 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031161
 protein coding gene Chr7:89805122-89874371 (-)
WSB/EiJ MGP_WSBEiJ_G0031717
 protein coding gene Chr7:103197434-103261943 (-)



Homology
more
  • Human Ortholog
    MRPL48, mitochondrial ribosomal protein L48
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL48, mitochondrial ribosomal protein L48
  • Synonyms
    CGI-118, HSPC290, L48MT, mL48, MRP-L48
  • Links
    NCBI Gene ID: 51642
    neXtProt AC: NX_Q96GC5
    UniProt: Q96GC5

  • Chr Location
    11q13.4; chr11:73787872-73865133 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    31
  • Chemically induced (other)
    1
  • Gene trapped
    27
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Mrpl48
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    24 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    13
  • cDNA Data
    14
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52443 NCBI Gene Model | MGI Sequence Detail 62523 C57BL/6J ±  kb
transcript NR_003559 RefSeq | MGI Sequence Detail 4555 C57BL/6  
polypeptide Q8JZS9 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916414
References
more
  • Summaries
    All 43
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory