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Atp6v0e Gene Detail
Summary
  • Symbol
    Atp6v0e
  • Name
    ATPase, H+ transporting, lysosomal V0 subunit E
  • Synonyms
    Atp6k, lysosomal 9kDa, M9.2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328318
    NCBI Gene: 11974
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26895370-26918621 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    779 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328318
 protein coding gene Chr17:26882205-26918621 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023404
 protein coding gene Chr17:25868001-25891890 (+)
A/J MGP_AJ_G0023363
 protein coding gene Chr17:25070148-25093412 (+)
AKR/J MGP_AKRJ_G0023329
 protein coding gene Chr17:25199207-25225578 (+)
BALB/cJ MGP_BALBcJ_G0023368
 protein coding gene Chr17:25325042-25348177 (+)
C3H/HeJ MGP_C3HHeJ_G0023128
 protein coding gene Chr17:25595349-25619386 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023808
 protein coding gene Chr17:26917154-26947031 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021283
 protein coding gene Chr17:22528011-22551673 (+)
CAST/EiJ MGP_CASTEiJ_G0022629
 protein coding gene Chr17:25528866-25553414 (+)
CBA/J MGP_CBAJ_G0023103
 protein coding gene Chr17:27902809-27930260 (+)
DBA/2J MGP_DBA2J_G0023233
 protein coding gene Chr17:24661205-24684388 (+)
FVB/NJ MGP_FVBNJ_G0023203
 protein coding gene Chr17:24436565-24460114 (+)
LP/J MGP_LPJ_G0023310
 protein coding gene Chr17:26130277-26153499 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023222
 protein coding gene Chr17:27425982-27451749 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023850
 protein coding gene Chr17:25555100-25582821 (+)
PWK/PhJ MGP_PWKPhJ_G0022378
 protein coding gene Chr17:23456279-23481283 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022196
 protein coding gene Chr17:23625104-23647253 (+)
WSB/EiJ MGP_WSBEiJ_G0022692
 protein coding gene Chr17:25605554-25629664 (+)



Homology
more
  • Human Ortholog
    ATP6V0E1, ATPase H+ transporting V0 subunit e1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP6V0E1, ATPase H+ transporting V0 subunit e1
  • Synonyms
    ATP6H, ATP6V0E, M9.2, Vma21, Vma21p
  • Links
    NCBI Gene ID: 8992
    neXtProt AC: NX_O15342
    UniProt: O15342

  • Chr Location
    5q35.1; chr5:172983771-173035445 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    19
  • Endonuclease-mediated
    3
  • Gene trapped
    13
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    2 involving Atp6v0e
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    846
  • Tissues
    103
  • cDNA Data
    109
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 11974 NCBI Gene Model | MGI Sequence Detail 23252 C57BL/6J ±  kb
transcript NM_025272 RefSeq | MGI Sequence Detail 800 Not Specified  
polypeptide Q9CQD8 UniProt | EBI | MGI Sequence Detail 81 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 110
    cDNA 110

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:47435 Ludwig J, et al., Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules. J Biol Chem. 1998 May 1;273(18):10939-47
  • Latest
    J:194116 Flachs P, et al., Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet. 2012;8(11):e1003044
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory