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Sprr2k Gene Detail
Summary
  • Symbol
    Sprr2k
  • Name
    small proline-rich protein 2K
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330344
    NCBI Gene: 20765
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92339889-92341232 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    96 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330344
 protein coding gene Chr3:92339889-92341234 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027496
 protein coding gene Chr3:92878146-92879489 (+)
A/J MGP_AJ_G0027463
 protein coding gene Chr3:89954980-89956323 (+)
AKR/J MGP_AKRJ_G0027428
 protein coding gene Chr3:92062873-92064216 (+)
BALB/cJ MGP_BALBcJ_G0027471
 protein coding gene Chr3:89769058-89770402 (+)
C3H/HeJ MGP_C3HHeJ_G0027211
 protein coding gene Chr3:92288242-92289585 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027915
 protein coding gene Chr3:96417218-96418561 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0026658
 protein coding gene Chr3:91699714-91701072 (+)
CBA/J MGP_CBAJ_G0027185
 protein coding gene Chr3:99713520-99714863 (+)
DBA/2J MGP_DBA2J_G0027323
 protein coding gene Chr3:89275944-89277287 (+)
FVB/NJ MGP_FVBNJ_G0027291
 protein coding gene Chr3:87448879-87450222 (+)
LP/J MGP_LPJ_G0027431
 protein coding gene Chr3:94095976-94097319 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027315
 protein coding gene Chr3:105972258-105973601 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027974
 protein coding gene Chr3:91793442-91794785 (+)
PWK/PhJ MGP_PWKPhJ_G0026391
 protein coding gene Chr3:89163472-89164817 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026210
 protein coding gene Chr3:90129311-90129898 (+)
WSB/EiJ MGP_WSBEiJ_G0026741
 protein coding gene Chr3:92183205-92184548 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054215 Ensembl Gene Model | MGI Sequence Detail 1344 C57BL/6J ±  kb
transcript ENSMUST00000067102 Ensembl | MGI Sequence Detail 637 Not Applicable  
polypeptide ENSMUSP00000063287 Ensembl | MGI Sequence Detail 68 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:113697 Gibbs S, et al., Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. Genomics. 1993 Jun;16(3):630-7
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory