Igkv8-16 Gene Detail

Summary

• Symbol
  Igkv8-16
• Name
  immunoglobulin kappa variable 8-16

• Feature Type
  gene segment
• IDs
  MGI:1330843
  NCBI Gene: 640340
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr6:70363656-70364222 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 31.89 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  102 from dbSNP Build 142
• Strain Annotations
  11

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1330843	gene segment	Chr6:70363656-70364236 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0000171	gene segment	Chr6:70529379-70787200 (-)
A/J	MGP_AJ_G0000156	gene segment	Chr6:68000685-68001265 (-)
AKR/J	MGP_AKRJ_G0000152	gene segment	Chr6:69807527-69808107 (-)
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0000104	gene segment	Chr6:114432638-114433211 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0000213	gene segment	Chr6:72605918-72606498 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0000149	gene segment	Chr6:75227553-75228112 (-)
DBA/2J	MGP_DBA2J_G0000144	gene segment	Chr6:67232071-67232644 (-)
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0000174	gene segment	Chr6:70375312-70375788 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0000111	gene segment	Chr6:68578127-68578710 (-)
WSB/EiJ	MGP_WSBEiJ_G0000153	gene segment	Chr6:70162610-70163190 (-)

Homology

• Human Ortholog
  IGKV4-1, immunoglobulin kappa variable 4-1

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IGKV4-1, immunoglobulin kappa variable 4-1
  
• Synonyms
  B3, IGKV41
• Links
  HGNC:5834

  NCBI Gene ID: 28908

  UniProt: P06312

  
  
• Chr Location
  2p11.2; chr2:88885397-88886153 (+)  GRCh38

---

• MGI Vertebrate Homology
  Igkv8-16 stringent orthology
  1 human;1 mouse;1 zebrafish
  
• HCOP
  vertebrate homology predictions: IGKV4-1
• Gene Tree
  Igkv8-16
  

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  19
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000076591 (Evidence)
• NCBI Gene
  640340

Representative Sequences			Length	Strain/Species
genomic	640340	NCBI Gene Model | MGI Sequence Detail	567	C57BL/6J
transcript	BC082779	GenBank | ENA | DDBJ | MGI Sequence Detail	1020	CZECHII
polypeptide	A0A0G2JDG9	UniProt | EBI | MGI Sequence Detail	121	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR003599 Immunoglobulin subtype
  IPR050150 Immunoglobulin Variable Light Chain
  IPR013106 Immunoglobulin V-set domain

Molecular
Reagents

• All nucleic 5

  Genomic 4

  cDNA 1

  
  

  Microarray probesets 1

References

• Summaries
  All 8
• Earliest
  J:47632 Kirschbaum T, et al., The 3' part of the immunoglobulin kappa locus of the mouse. Eur J Immunol. 1998 May;28(5):1458-66
• Latest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61