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Igkv8-19 Gene Detail
Summary
  • Symbol
    Igkv8-19
  • Name
    immunoglobulin kappa variable 8-19
  • Feature Type
    gene segment
  • IDs
    MGI:1330844
    NCBI Gene: 232065
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr6:70317860-70318432 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 31.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    6
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330844
 gene segment Chr6:70317860-70318437 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000175
 gene segment Chr6:70786613-70786917 (-)
A/J MGP_AJ_G0000154
 gene segment Chr6:67951791-67952314 (-)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0000211
 gene segment Chr6:72495584-72496161 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0000145
 gene segment Chr6:66782114-66782650 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0000130
 gene segment Chr6:66164362-66164935 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV4-1, immunoglobulin kappa variable 4-1
  • Synonyms
    B3, IGKV41
  • Links
    NCBI Gene ID: 28908
    UniProt: P06312

  • Chr Location
    2p11.2; chr2:88885397-88886153 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    19
  • RefSeq
    1
  • UniProt
    3
Representative SequencesLengthStrain/SpeciesFlank
genomic 232065 NCBI Gene Model | MGI Sequence Detail 573 C57BL/6J ±  kb
transcript Z70661 GenBank | ENA | DDBJ | MGI Sequence Detail 783 Not Specified  
polypeptide A0A0G2JFN8 UniProt | EBI | MGI Sequence Detail 121 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR050150 Immunoglobulin Variable Light Chain
    IPR013106 Immunoglobulin V-set domain
  • GlyGen
    A0A140T8M4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 4
    Genomic 4

    Microarray probesets 2
References
more
  • Summaries
    All 9
    Gene Ontology 1
  • Earliest
    J:47632 Kirschbaum T, et al., The 3' part of the immunoglobulin kappa locus of the mouse. Eur J Immunol. 1998 May;28(5):1458-66
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory