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Igkv3-4 Gene Detail
Summary
  • Symbol
    Igkv3-4
  • Name
    immunoglobulin kappa variable 3-4
  • Feature Type
    gene segment
  • IDs
    MGI:1330855
    NCBI Gene: 626347
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:70648773-70649361 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 32.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    269 from dbSNP Build 142
  • Strain Annotations
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330855
 gene segment Chr6:70648772-70649361 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0000223
 gene segment Chr6:72951061-72951650 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0000205
 gene segment Chr6:70161672-70162261 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0000158
 gene segment Chr6:70473899-70474489 (+)



Homology
more
  • Human Ortholog
    IGKV3-11, immunoglobulin kappa variable 3-11
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGKV3-11, immunoglobulin kappa variable 3-11
  • Synonyms
    IGKV311, L6
  • Links
    NCBI Gene ID: 28914

  • Chr Location
    2p11.2; chr2:89027171-89027731 (-)  GRCh38
  • Human Ortholog
    IGKV3-15, immunoglobulin kappa variable 3-15
  • Synonyms
    IGKV315, L2
  • Links
    NCBI Gene ID: 28913
    UniProt: P01624

  • Chr Location
    2p11.2; chr2:89085177-89085787 (-)  GRCh38
  • Human Ortholog
    IGKV3-20, immunoglobulin kappa variable 3-20
  • Synonyms
    13K18, A27, IGKV320
  • Links
    NCBI Gene ID: 28912
    UniProt: P01619

  • Chr Location
    2p11.2; chr2:89142574-89143160 (-)  GRCh38
  • Human Ortholog
    IGKV3-7, immunoglobulin kappa variable 3-7 (non-functional)
  • Synonyms
    IGKV37, L10, L10a, Vh
  • Links
    NCBI Gene ID: 28915
    UniProt: A0A075B6H7

  • Chr Location
    2p11.2; chr2:88978468-88979081 (-)  GRCh38
  • Human Ortholog
    IGKV3D-11, immunoglobulin kappa variable 3D-11
  • Synonyms
    IGKV3D11, L20
  • Links
    NCBI Gene ID: 28876
    UniProt: A0A0A0MRZ8

  • Chr Location
    2p11.2; chr2:90172802-90173414 (+)  GRCh38
  • Human Ortholog
    IGKV3D-15, immunoglobulin kappa variable 3D-15
  • Synonyms
    IGKV3D15, L16, L16a, L16b, L16c
  • Links
    NCBI Gene ID: 28875
    UniProt: A0A087WSY6

  • Chr Location
    2p11.2; chr2:90114838-90115402 (+)  GRCh38
  • Human Ortholog
    IGKV3D-20, immunoglobulin kappa variable 3D-20
  • Synonyms
    A11, A11a, IGKV3D20
  • Links
    NCBI Gene ID: 28874
    UniProt: A0A0C4DH25

  • Chr Location
    2p11.2; chr2:90038848-90039479 (+)  GRCh38
  • Human Ortholog
    IGKV3D-7, immunoglobulin kappa variable 3D-7
  • Synonyms
    IGKV3D7, L25
  • Links
    NCBI Gene ID: 28877
    UniProt: A0A0C4DH55

  • Chr Location
    2p11.2; chr2:90234812-90235370 (+)  GRCh38
  • Human Ortholog
    IGKV3OR2-268, immunoglobulin kappa variable 3/OR2-268 (non-functional)
  • Synonyms
    IGKV268, IGKV3OR2268, IGKV3OR2-268A, IGKV3OR2268A
  • Links
    NCBI Gene ID: 3523

  • Chr Location
    2p12; chr2:87338511-87339035 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
  • All Sequences
    14
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 626347 NCBI Gene Model | MGI Sequence Detail 589 C57BL/6J ±  kb
transcript BC108385 GenBank | ENA | DDBJ | MGI Sequence Detail 961 FVB/N  
polypeptide A0A140T8Q4 UniProt | EBI | MGI Sequence Detail 119 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR050150 Immunoglobulin Variable Light Chain
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 5
    Genomic 4
    cDNA 1
References
more
  • Summaries
    All 10
    Gene Ontology 2
  • Earliest
    J:47632 Kirschbaum T, et al., The 3' part of the immunoglobulin kappa locus of the mouse. Eur J Immunol. 1998 May;28(5):1458-66
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory