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Trpt1 Gene Detail
Summary
  • Symbol
    Trpt1
  • Name
    tRNA phosphotransferase 1
  • Synonyms
    EST-MNCb3719, MGC:41710, TPT1, Tpt1h
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333115
    NCBI Gene: 107328
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:6973499-6976414 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 5.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333115
 protein coding gene Chr19:6970046-6977689 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024780
 protein coding gene Chr19:4094069-4096982 (+)
A/J MGP_AJ_G0024747
 protein coding gene Chr19:3759755-3762668 (+)
AKR/J MGP_AKRJ_G0024720
 protein coding gene Chr19:3883367-3886280 (+)
BALB/cJ MGP_BALBcJ_G0024747
 protein coding gene Chr19:3870154-3873067 (+)
C3H/HeJ MGP_C3HHeJ_G0024515
 protein coding gene Chr19:4005642-4008555 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025193
 protein coding gene Chr19:4185915-4188828 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022627
 protein coding gene Chr19:3665776-3668624 (+)
CAST/EiJ MGP_CASTEiJ_G0023987
 protein coding gene Chr19:3914050-3916963 (+)
CBA/J MGP_CBAJ_G0024487
 protein coding gene Chr19:4240901-4243814 (+)
DBA/2J MGP_DBA2J_G0024614
 protein coding gene Chr19:3731141-3734054 (+)
FVB/NJ MGP_FVBNJ_G0024579
 protein coding gene Chr19:3762663-3765565 (+)
LP/J MGP_LPJ_G0024700
 protein coding gene Chr19:3956050-3958963 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024609
 protein coding gene Chr19:4145803-4148716 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025241
 protein coding gene Chr19:4021566-4024479 (+)
PWK/PhJ MGP_PWKPhJ_G0023733
 protein coding gene Chr19:3775962-3778887 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023537
 protein coding gene Chr19:3834880-3837791 (+)
WSB/EiJ MGP_WSBEiJ_G0024049
 protein coding gene Chr19:3923379-3926292 (+)



Homology
more
  • Human Ortholog
    TRPT1, tRNA phosphotransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Mice homozygous for a knock-out allele exhibit normal glucose tolerance and translation of tyrosine-rich proteins.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    12
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047656 Ensembl Gene Model | MGI Sequence Detail 2916 C57BL/6J ±  kb
transcript ENSMUST00000088223 Ensembl | MGI Sequence Detail 1103 Not Applicable  
polypeptide ENSMUSP00000085555 Ensembl | MGI Sequence Detail 249 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2147684, MGI:2183030
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:51223 Spinelli SL, et al., A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14136-41
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory