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Mrpl10 Gene Detail
Summary
  • Symbol
    Mrpl10
  • Name
    mitochondrial ribosomal protein L10
  • Synonyms
    0610040E02Rik, MGC:28763, MRP-L8, Rpml8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333801
    NCBI Gene: 107732
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96932408-96940039 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 60.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    274 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333801
 protein coding gene Chr11:96932386-96940039 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019022
 protein coding gene Chr11:99420003-99430180 (+)
A/J MGP_AJ_G0018990
 protein coding gene Chr11:95350783-95358475 (+)
AKR/J MGP_AKRJ_G0018960
 protein coding gene Chr11:98306755-98314734 (+)
BALB/cJ MGP_BALBcJ_G0018963
 protein coding gene Chr11:95839792-95847445 (+)
C3H/HeJ MGP_C3HHeJ_G0018777
 protein coding gene Chr11:98417993-98425646 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019415
 protein coding gene Chr11:102503446-102511099 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017046
 protein coding gene Chr11:92812449-92820418 (+)
CAST/EiJ MGP_CASTEiJ_G0018330
 protein coding gene Chr11:99273602-99282386 (+)
CBA/J MGP_CBAJ_G0018748
 protein coding gene Chr11:106715730-106723424 (+)
DBA/2J MGP_DBA2J_G0018856
 protein coding gene Chr11:94901374-94909027 (+)
FVB/NJ MGP_FVBNJ_G0018845
 protein coding gene Chr11:94380276-94387929 (+)
LP/J MGP_LPJ_G0018926
 protein coding gene Chr11:99947650-99955328 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018872
 protein coding gene Chr11:106634013-106641633 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019455
 protein coding gene Chr11:98601043-98608696 (+)
PWK/PhJ MGP_PWKPhJ_G0018102
 protein coding gene Chr11:95874259-95882129 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017892
 protein coding gene Chr11:98325930-98334781 (+)
WSB/EiJ MGP_WSBEiJ_G0018380
 protein coding gene Chr11:98506816-98514469 (+)



Homology
more
  • Human Ortholog
    MRPL10, mitochondrial ribosomal protein L10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL10, mitochondrial ribosomal protein L10
  • Synonyms
    L10MT, MRP-L10, MRP-L8, MRPL8, RPML8, uL10m
  • Links
    NCBI Gene ID: 124995
    neXtProt AC: NX_Q7Z7H8
    UniProt: Q7Z7H8

  • Chr Location
    17q21.32
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    13
  • cDNA Data
    112
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 107732 NCBI Gene Model | MGI Sequence Detail 7632 C57BL/6J ±  kb
transcript NM_026154 RefSeq | MGI Sequence Detail 1686 C57BL/6  
polypeptide Q3TBW2 UniProt | EBI | MGI Sequence Detail 262 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010572 large ribosomal subunit protein uL10m
    (term hierarchy)
  • InterPro Domains
    IPR047865 Large ribosomal subunit protein uL10, bacterial type
    IPR043141 Large ribosomal subunit protein uL10-like domain superfamily
  • GlyGen
    Q3TBW2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 113
    cDNA 112
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1914686, MGI:2144641
References
more
  • Summaries
    All 46
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:51617 Goldschmidt-Reisin S, et al., Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequences. J Biol Chem. 1998 Dec 25;273(52):34828-36
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory