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Myh13 Gene Detail
Summary
  • Symbol
    Myh13
  • Name
    myosin, heavy polypeptide 13, skeletal muscle
  • Synonyms
    EO Myosin, extraocular myosin, MyHC-eo
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339967
    NCBI Gene: 544791
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:67217929-67262413 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 40.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1541 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1339967
 protein coding gene Chr11:67212484-67262413 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018490
 protein coding gene Chr11:67625605-67678902 (+)
A/J MGP_AJ_G0018459
 protein coding gene Chr11:65085599-65137982 (+)
AKR/J MGP_AKRJ_G0018428
 protein coding gene Chr11:67036647-67091518 (+)
BALB/cJ MGP_BALBcJ_G0018430
 protein coding gene Chr11:65365540-65414731 (+)
C3H/HeJ MGP_C3HHeJ_G0018243
 protein coding gene Chr11:67043591-67094477 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018882
 protein coding gene Chr11:69676401-69733942 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016526
 protein coding gene Chr11:62040409-62091437 (+)
CAST/EiJ MGP_CASTEiJ_G0017799
 protein coding gene Chr11:67268850-67319324 (+)
CBA/J MGP_CBAJ_G0018217
 protein coding gene Chr11:72749436-72811528 (+)
DBA/2J MGP_DBA2J_G0018326
 protein coding gene Chr11:64691867-64740157 (+)
FVB/NJ MGP_FVBNJ_G0018316
 protein coding gene Chr11:64293053-64344663 (+)
LP/J MGP_LPJ_G0018397
 protein coding gene Chr11:68172836-68224459 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018339
 protein coding gene Chr11:73540521-73593430 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018923
 protein coding gene Chr11:67280031-67334263 (+)
PWK/PhJ MGP_PWKPhJ_G0017574
 protein coding gene Chr11:65295979-65347590 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017362
 protein coding gene Chr11:67097254-67151732 (+)
WSB/EiJ MGP_WSBEiJ_G0017852
 protein coding gene Chr11:66887163-66936814 (+)



Homology
more
  • Human Ortholog
    MYH13, myosin heavy chain 13
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYH13, myosin heavy chain 13
  • Synonyms
    MyHC-eo, MyHC-IIL
  • Links
    NCBI Gene ID: 8735
    neXtProt AC: NX_Q9UKX3
    UniProt: Q9UKX3

  • Chr Location
    17p13.1; chr17:10300865-10373130 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 544791 NCBI Gene Model | MGI Sequence Detail 44485 C57BL/6J ±  kb
transcript NM_001081250 RefSeq | MGI Sequence Detail 5902 ZRU/MplStud  
polypeptide NP_001074719 RefSeq | MGI Sequence Detail 1938 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR014751 DNA repair protein XRCC4-like, C-terminal
    IPR036961 Kinesin motor domain superfamily
    IPR042702 Myosin-13, motor domain
    IPR001609 Myosin head, motor domain
    IPR004009 Myosin, N-terminal, SH3-like
    IPR008989 Myosin S1 fragment, N-terminal
    IPR002928 Myosin tail
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 9
    Genomic 6
    cDNA 2
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory