Zfp207 MGI Mouse Gene Detail - MGI:1340045

Symbol

Zfp207
Name

zinc finger protein 207
Synonyms

8430401D15Rik, Zep

Feature Type

protein coding gene
IDs

MGI:1340045
NCBI Gene: 22680
Alliance

gene page
Transcription Start Sites

13 TSS

Sequence Map

Chr11:80274105-80296559 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 47.83 cM, cytoband B5
Mapping Data

3 experiments

SNPs within 2kb

409 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1340045	protein coding gene	Chr11:80274105-80299387 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018812	protein coding gene	Chr11:81544969-81568127 (+)
A/J	MGP_AJ_G0018779	protein coding gene	Chr11:78413803-78436049 (+)
AKR/J	MGP_AKRJ_G0018749	protein coding gene	Chr11:80766339-80788706 (+)
BALB/cJ	MGP_BALBcJ_G0018752	protein coding gene	Chr11:78808199-78831402 (+)
C3H/HeJ	MGP_C3HHeJ_G0018566	protein coding gene	Chr11:80815854-80838173 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019204	protein coding gene	Chr11:84032945-84055499 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016838	protein coding gene	Chr11:75344129-75366435 (+)
CAST/EiJ	MGP_CASTEiJ_G0018121	protein coding gene	Chr11:81304824-81326481 (+)
CBA/J	MGP_CBAJ_G0018537	protein coding gene	Chr11:87710236-87734515 (+)
DBA/2J	MGP_DBA2J_G0018645	protein coding gene	Chr11:77968048-77991183 (+)
FVB/NJ	MGP_FVBNJ_G0018634	protein coding gene	Chr11:77531421-77553841 (+)
LP/J	MGP_LPJ_G0018715	protein coding gene	Chr11:82068683-82091081 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018661	protein coding gene	Chr11:87975650-87998777 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019244	protein coding gene	Chr11:81021768-81045234 (+)
PWK/PhJ	MGP_PWKPhJ_G0017891	protein coding gene	Chr11:78780570-78803323 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017682	protein coding gene	Chr11:80614483-80637208 (+)
WSB/EiJ	MGP_WSBEiJ_G0018173	protein coding gene	Chr11:80856239-80879152 (+)

Human Ortholog

ZNF207, zinc finger protein 207

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF207, zinc finger protein 207
Synonyms

BuGZ, hBuGZ
Links

HGNC:12998

NCBI Gene ID: 7756

neXtProt AC: NX_O43670

UniProt: O43670
Chr Location

17q11.2; chr17:32350132-32381885 (+) GRCh38

MGI Vertebrate Homology

Zfp207 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: ZNF207
Gene Tree

Zfp207

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Phenotype Summary

5 phenotypes from 1 allele in 1 genetic background
19 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

30
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

25
Targeted

3
Genomic Mutations

2 involving Zfp207
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

28 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

39
GO References

9

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

859
Tissues

114
cDNA Data

21
Literature Summary

16

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase znf207

ZFIN znf207b

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All Sequences

126
RefSeq

60
UniProt

4
CCDS

CCDS48863.1, CCDS48864.1, CCDS48865.1

Ensembl

ENSMUSG00000017421 (Evidence)
NCBI Gene

22680

			Length	Strain/Species	Flank
genomic	ENSMUSG00000017421	Ensembl Gene Model \| MGI Sequence Detail	22455	C57BL/6J	± kb
transcript	ENSMUST00000053740	Ensembl \| MGI Sequence Detail	1562	Not Applicable
polypeptide	ENSMUSP00000054168	Ensembl \| MGI Sequence Detail	495	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000017748 BUB3-interacting and GLEBS motif-containing protein ZNF207

(term hierarchy)
InterPro Domains

IPR013087 Zinc finger C2H2-type
GlyGen

Q9JMD0 12 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (11 sites)

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All nucleic 29

cDNA 26

Primer pair 3

Microarray probesets 11

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MGI:1918717

Summaries

All 65

Developmental Gene Expression 16

Gene Ontology 9

Phenotypes 19
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Zfp207:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr103516	Chr11:80274125-80274130 (+)	23 bp
Tssr103517	Chr11:80274135-80274162 (+)	44 bp
Tssr103518	Chr11:80274224-80274241 (+)	128 bp
Tssr103519	Chr11:80274868-80274874 (+)	766 bp
Tssr103520	Chr11:80277344-80277351 (+)	3,243 bp
Tssr103521	Chr11:80279900-80279918 (+)	5,804 bp
Tssr103522	Chr11:80280242-80280245 (+)	6,139 bp
Tssr103523	Chr11:80282654-80282677 (+)	8,561 bp
Tssr103524	Chr11:80282755-80282774 (+)	8,660 bp
Tssr103525	Chr11:80285101-80285239 (+)	11,065 bp
Tssr103526	Chr11:80286361-80286374 (+)	12,263 bp
Tssr103527	Chr11:80290454-80290460 (+)	16,352 bp
Tssr103528	Chr11:80294171-80294175 (+)	20,068 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24