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Fhl3 Gene Detail
Summary
  • Symbol
    Fhl3
  • Name
    four and a half LIM domains 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341092
    NCBI Gene: 14201
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:124594494-124602404 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 57.88 cM, cytoband D1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    243 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341092
 protein coding gene Chr4:124589750-124602404 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028751
 protein coding gene Chr4:126245499-126252694 (+)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0028733
 protein coding gene Chr4:121872583-121879700 (+)
C3H/HeJ MGP_C3HHeJ_G0028447
 protein coding gene Chr4:124704778-124712074 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029175
 protein coding gene Chr4:131112972-131120357 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026448
 protein coding gene Chr4:114471993-114480905 (+)
CAST/EiJ MGP_CASTEiJ_G0027880
 protein coding gene Chr4:122759451-122767352 (+)
CBA/J MGP_CBAJ_G0028413
 protein coding gene Chr4:134366320-134377407 (+)
DBA/2J MGP_DBA2J_G0028562
 protein coding gene Chr4:121773338-121782951 (+)
FVB/NJ MGP_FVBNJ_G0028529
 protein coding gene Chr4:120394119-120402463 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0028555
 protein coding gene Chr4:139364317-139373344 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029213
 protein coding gene Chr4:124976701-124983644 (+)
PWK/PhJ MGP_PWKPhJ_G0027601
 protein coding gene Chr4:118184681-118192695 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027427
 protein coding gene Chr4:120747222-120758276 (+)
WSB/EiJ MGP_WSBEiJ_G0027960
 protein coding gene Chr4:125048356-125056317 (+)



Homology
more
  • Human Ortholog
    FHL3, four and a half LIM domains 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FHL3, four and a half LIM domains 3
  • Synonyms
    SLIM2
  • Links
    NCBI Gene ID: 2275
    neXtProt AC: NX_Q13643
    UniProt: Q13643

  • Chr Location
    1p34.3; chr1:37996764-38005606 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    768
  • Tissues
    57
  • cDNA Data
    7
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032643 Ensembl Gene Model | MGI Sequence Detail 7911 C57BL/6J ±  kb
transcript ENSMUST00000038684 Ensembl | MGI Sequence Detail 1664 Not Applicable  
polypeptide ENSMUSP00000040150 Ensembl | MGI Sequence Detail 289 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:53041 Morgan MJ, et al., The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle. Biochem Biophys Res Commun. 1999 Feb 16;255(2):245-50
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory