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Znrf4 Gene Detail
Summary
  • Symbol
    Znrf4
  • Name
    zinc and ring finger 4
  • Synonyms
    spzn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341258
    NCBI Gene: 20834
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:56818248-56819431 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 29.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    81 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341258
 protein coding gene Chr17:56818248-56819483 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023927
 protein coding gene Chr17:58210668-58211903 (-)
A/J MGP_AJ_G0023885
 protein coding gene Chr17:56614226-56615461 (-)
AKR/J MGP_AKRJ_G0023854
 protein coding gene Chr17:57315151-57316386 (-)
BALB/cJ MGP_BALBcJ_G0023886
 protein coding gene Chr17:56435783-56437018 (-)
C3H/HeJ MGP_C3HHeJ_G0023650
 protein coding gene Chr17:58040319-58041554 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024332
 protein coding gene Chr17:60470712-60471947 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021778
 protein coding gene Chr17:53097566-53098801 (-)
CAST/EiJ MGP_CASTEiJ_G0023132
 protein coding gene Chr17:58329380-58330615 (-)
CBA/J MGP_CBAJ_G0023626
 protein coding gene Chr17:62832184-62833419 (-)
DBA/2J MGP_DBA2J_G0023754
 protein coding gene Chr17:55321017-55322252 (-)
FVB/NJ MGP_FVBNJ_G0023720
 protein coding gene Chr17:54853798-54855033 (-)
LP/J MGP_LPJ_G0023836
 protein coding gene Chr17:58897327-58898562 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023748
 protein coding gene Chr17:62313198-62314433 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024376
 protein coding gene Chr17:57678419-57679654 (-)
PWK/PhJ MGP_PWKPhJ_G0022878
 protein coding gene Chr17:54676872-54678107 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022689
 protein coding gene Chr17:54436696-54437931 (-)
WSB/EiJ MGP_WSBEiJ_G0023198
 protein coding gene Chr17:58288183-58289418 (-)



Homology
more
  • Human Ortholog
    ZNRF4, zinc and ring finger 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNRF4, zinc and ring finger 4
  • Synonyms
    RNF204, SPERIZIN, spzn, Ssrzf1
  • Links
    NCBI Gene ID: 148066
    neXtProt AC: NX_Q8WWF5
    UniProt: Q8WWF5

  • Chr Location
    19p13.3; chr19:5455417-5456856 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    15
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044526 Ensembl Gene Model | MGI Sequence Detail 1184 C57BL/6J ±  kb
transcript ENSMUST00000052211 Ensembl | MGI Sequence Detail 1184 Not Applicable  
polypeptide ENSMUSP00000059715 Ensembl | MGI Sequence Detail 327 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 2
  • Earliest
    J:54668 Fujii T, et al., Sperizin is a murine RING zinc-finger protein specifically expressed in Haploid germ cells. Genomics. 1999 Apr 1;57(1):94-101
  • Latest
    J:351297 Ge T, et al., Coiled-coil domain containing 159 is required for spermatid head and tail assembly in mice. Biol Reprod. 2024 May 9;110(5):877-894
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory