Tex10 MGI Mouse Gene Detail - MGI:1344413

Symbol

Tex10
Name

testis expressed gene 10
Synonyms

2610206N19Rik, 2810462N03Rik, clone 18330, MGC:11792

Feature Type

protein coding gene
IDs

MGI:1344413
NCBI Gene: 269536
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr4:48430858-48473459 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 26.13 cM
Mapping Data

3 experiments

SNPs within 2kb

789 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1344413	protein coding gene	Chr4:48430805-48473492 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0028274	protein coding gene	Chr4:46855677-46902005 (-)
A/J	MGP_AJ_G0028234	protein coding gene	Chr4:45108609-45151574 (-)
AKR/J	MGP_AKRJ_G0028183	protein coding gene	Chr4:46255806-46298308 (-)
BALB/cJ	MGP_BALBcJ_G0028253	protein coding gene	Chr4:45225285-45269059 (-)
C3H/HeJ	MGP_C3HHeJ_G0027974	protein coding gene	Chr4:46828412-46874025 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0028694	protein coding gene	Chr4:48546146-48590857 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026003	protein coding gene	Chr4:42453312-42501983 (-)
CAST/EiJ	MGP_CASTEiJ_G0027413	protein coding gene	Chr4:46428628-46478471 (-)
CBA/J	MGP_CBAJ_G0027940	protein coding gene	Chr4:50116012-50162210 (-)
DBA/2J	MGP_DBA2J_G0028090	protein coding gene	Chr4:44992847-45035438 (-)
FVB/NJ	MGP_FVBNJ_G0028057	protein coding gene	Chr4:44260342-44302742 (-)
LP/J	MGP_LPJ_G0028189	protein coding gene	Chr4:46915347-46958606 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028081	protein coding gene	Chr4:53121786-53168071 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028729	protein coding gene	Chr4:46454624-46498291 (-)
PWK/PhJ	MGP_PWKPhJ_G0027138	protein coding gene	Chr4:45119330-45162185 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0026966	protein coding gene	Chr4:45967566-46021820 (-)
WSB/EiJ	MGP_WSBEiJ_G0027491	protein coding gene	Chr4:46387799-46431667 (-)

Human Ortholog

TEX10, testis expressed 10

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TEX10, testis expressed 10
Synonyms

bA208F1.2, Ipi1
Links

HGNC:25988

NCBI Gene ID: 54881

neXtProt AC: NX_Q9NXF1

UniProt: Q9NXF1
Chr Location

9q31.1; chr9:100302077-100352942 (-) GRCh38

MGI Vertebrate Homology

Tex10 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TEX10
Gene Tree

Tex10

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

16
Endonuclease-mediated

2
Gene trapped

11
Targeted

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

51 strains or lines available

Mice homozygous for a knock-out allele exhibit embryonic lethality prior to E7.5 with impaired inner cell mass proliferation in culture.

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All GO Annotations

8
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

115

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tex10

ZFIN tex10

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All Sequences

58
RefSeq

10
UniProt

3
CCDS

CCDS38760.1

Ensembl

ENSMUSG00000028345 (Evidence)
NCBI Gene

269536

			Length	Strain/Species	Flank
genomic	ENSMUSG00000028345	Ensembl Gene Model \| MGI Sequence Detail	42602	C57BL/6J	± kb
transcript	ENSMUST00000030030	Ensembl \| MGI Sequence Detail	3102	Not Applicable
polypeptide	ENSMUSP00000030030	Ensembl \| MGI Sequence Detail	928	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000016247 testis-expressed protein 10

(term hierarchy)
InterPro Domains

IPR011989 Armadillo-like helical

IPR016024 Armadillo-type fold

IPR021133 HEAT, type 2

IPR024679 Pre-rRNA-processing protein Ipi1, N-terminal

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All nucleic 117

Genomic 2

cDNA 115

Microarray probesets 4

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MGI:1917681, MGI:1920062, MGI:2446290

Summaries

All 37

Gene Ontology 5

Phenotypes 10
Earliest

J:50117 Morgan D, et al., Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse. (Erratum appears in v. 20, pg. 312). Nat Genet. 1998 Oct;20(2):149-56
Latest

J:224684 Ding J, et al., Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming. Cell Stem Cell. 2015 Jun 4;16(6):653-68

TSS for Tex10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr41645	Chr4:48473403-48473457 (-)	29 bp
Tssr41644	Chr4:48473382-48473401 (-)	67 bp
Tssr41643	Chr4:48473339-48473356 (-)	111 bp
Tssr41642	Chr4:48468791-48468819 (-)	4,654 bp
Tssr41641	Chr4:48442128-48442131 (-)	31,329 bp
Tssr41640	Chr4:48435099-48435108 (-)	38,355 bp
Tssr41639	Chr4:48435004-48435017 (-)	38,448 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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