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Tenm2 Gene Detail
Summary
  • Symbol
    Tenm2
  • Name
    teneurin transmembrane protein 2
  • Synonyms
    2610040L17Rik, 9330187F13Rik, D3Bwg1534e, mKIAA1127, Odz2, Ten-m2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345184
    NCBI Gene: 23964
  • Alliance
    gene page
  • Transcription Start Sites
    47 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:35897483-37126791 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 21.96 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    29866 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345184
 protein coding gene Chr11:35897483-37881486 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018159
 protein coding gene Chr11:34430103-35707744 (-)
A/J MGP_AJ_G0018132
 protein coding gene Chr11:33137954-34381818 (-)
AKR/J MGP_AKRJ_G0018096
 protein coding gene Chr11:34133705-35412710 (-)
BALB/cJ MGP_BALBcJ_G0018101
 protein coding gene Chr11:33300124-34539541 (-)
C3H/HeJ MGP_C3HHeJ_G0017914
 protein coding gene Chr11:34099512-35364306 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018555
 protein coding gene Chr11:35475585-36779340 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016210
 protein coding gene Chr11:31586911-32809518 (-)
CAST/EiJ MGP_CASTEiJ_G0017478
 protein coding gene Chr11:34082070-35363528 (-)
CBA/J MGP_CBAJ_G0017887
 protein coding gene Chr11:37170697-38553897 (-)
DBA/2J MGP_DBA2J_G0017997
 protein coding gene Chr11:32882020-34117091 (-)
FVB/NJ MGP_FVBNJ_G0017991
 protein coding gene Chr11:32733282-33966914 (-)
LP/J MGP_LPJ_G0018069
 protein coding gene Chr11:34650098-35911248 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018015
 protein coding gene Chr11:37880457-39198077 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018594
 protein coding gene Chr11:34158704-35420851 (-)
PWK/PhJ MGP_PWKPhJ_G0017259
 protein coding gene Chr11:32967628-34224420 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017051
 protein coding gene Chr11:33934395-35199400 (-)
WSB/EiJ MGP_WSBEiJ_G0017527
 protein coding gene Chr11:33933667-35214566 (-)



Homology
more
  • Human Ortholog
    TENM2, teneurin transmembrane protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TENM2, teneurin transmembrane protein 2
  • Synonyms
    ODZ2, ten-2, TEN2, TEN-M2, TNM2
  • Links
    NCBI Gene ID: 57451
    neXtProt AC: NX_Q9NT68
    UniProt: Q9NT68

  • Chr Location
    5q34; chr5:166979029-168264157 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    50
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1031
  • Tissues
    218
  • cDNA Data
    40
  • Literature Summary
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000049336 Ensembl Gene Model | MGI Sequence Detail 1229309 C57BL/6J ±  kb
    transcript ENSMUST00000057207 Ensembl | MGI Sequence Detail 8298 Not Applicable  
    polypeptide ENSMUSP00000052014 Ensembl | MGI Sequence Detail 2765 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      cDNA 43
      Primer pair 5
      Other 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-35806, MGI:107340, MGI:1919714, MGI:1924765
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 16
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:348278 Liakath-Ali K, et al., Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory