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Coro1b Gene Detail
Summary
  • Symbol
    Coro1b
  • Name
    coronin, actin binding protein 1B
  • Synonyms
    coronin 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345963
    NCBI Gene: 23789
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr19:4198618-4204034 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 3.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    19 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345963
 protein coding gene Chr19:4198610-4204034 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024650
 protein coding gene Chr19:986179-993024 (+)
A/J MGP_AJ_G0024616
 protein coding gene Chr19:950128-955687 (+)
AKR/J MGP_AKRJ_G0024589
 protein coding gene Chr19:975449-980859 (+)
BALB/cJ MGP_BALBcJ_G0024616
 protein coding gene Chr19:939131-945238 (+)
C3H/HeJ MGP_C3HHeJ_G0024384
 protein coding gene Chr19:970618-975929 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025064
 protein coding gene Chr19:1026456-1031882 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022493
 protein coding gene Chr19:892726-898139 (+)
CAST/EiJ MGP_CASTEiJ_G0023856
 protein coding gene Chr19:980351-986788 (+)
CBA/J MGP_CBAJ_G0024355
 protein coding gene Chr19:1081545-1089527 (+)
DBA/2J MGP_DBA2J_G0024483
 protein coding gene Chr19:910029-915678 (+)
FVB/NJ MGP_FVBNJ_G0024450
 protein coding gene Chr19:920685-926088 (+)
LP/J MGP_LPJ_G0024569
 protein coding gene Chr19:978968-985949 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024480
 protein coding gene Chr19:1029285-1035674 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025111
 protein coding gene Chr19:971920-977321 (+)
PWK/PhJ MGP_PWKPhJ_G0023602
 protein coding gene Chr19:962355-967842 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023407
 protein coding gene Chr19:952516-957863 (+)
WSB/EiJ MGP_WSBEiJ_G0023918
 protein coding gene Chr19:960260-965675 (+)



Homology
more
  • Human Ortholog
    CORO1B, coronin 1B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CORO1B, coronin 1B
  • Synonyms
    CORONIN-2
  • Links
    NCBI Gene ID: 57175
    neXtProt AC: NX_Q9BR76
    UniProt: Q9BR76

  • Chr Location
    11q13.2; chr11:67435510-67443821 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    6 phenotype references
Mice homozygous for a knock-out allele exhibit normal mast cell degranulation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    62
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    756
  • Tissues
    49
  • cDNA Data
    207
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024835 Ensembl Gene Model | MGI Sequence Detail 5417 C57BL/6J ±  kb
transcript ENSMUST00000008893 Ensembl | MGI Sequence Detail 1888 Not Applicable  
polypeptide ENSMUSP00000008893 Ensembl | MGI Sequence Detail 484 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 211
    cDNA 208
    Primer pair 1
    Other 2

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:50558 Okumura M, et al., Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. DNA Cell Biol. 1998 Sep;17(9):779-87
  • Latest
    J:346416 Koopmans F, et al., SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron. 2019 Jul 17;103(2):217-234.e4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory