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Eci2 Gene Detail
Summary
  • Symbol
    Eci2
  • Name
    enoyl-Coenzyme A delta isomerase 2
  • Synonyms
    ACBD2, DRS1, HCA88, Peci
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346064
    NCBI Gene: 23986
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:35161731-35211079 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 14.23 cM, cytoband A4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1097 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346064
 protein coding gene Chr13:35161731-35211098 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020457
 protein coding gene Chr13:33123236-33144005 (-)
A/J MGP_AJ_G0020411
 protein coding gene Chr13:32102680-32153635 (-)
AKR/J MGP_AKRJ_G0020389
 protein coding gene Chr13:32897912-32926506 (-)
BALB/cJ MGP_BALBcJ_G0020407
 protein coding gene Chr13:32199304-32246301 (-)
C3H/HeJ MGP_C3HHeJ_G0020206
 protein coding gene Chr13:32826000-32873686 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020839
 protein coding gene Chr13:34265440-34333637 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018427
 protein coding gene Chr13:30434367-30450708 (-)
CAST/EiJ MGP_CASTEiJ_G0019721
 protein coding gene Chr13:32510843-32530602 (-)
CBA/J MGP_CBAJ_G0020167
 protein coding gene Chr13:35731782-35756614 (-)
DBA/2J MGP_DBA2J_G0020289
 protein coding gene Chr13:31671931-31726829 (-)
FVB/NJ MGP_FVBNJ_G0020268
 protein coding gene Chr13:31232930-31249950 (-)
LP/J MGP_LPJ_G0020364
 protein coding gene Chr13:33376052-33402522 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020298
 protein coding gene Chr13:35841995-35910019 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020883
 protein coding gene Chr13:32527342-32567216 (-)
PWK/PhJ MGP_PWKPhJ_G0019476
 protein coding gene Chr13:31798615-31815960 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019303
 protein coding gene Chr13:31183581-31218540 (-)
WSB/EiJ MGP_WSBEiJ_G0019783
 protein coding gene Chr13:32917783-32934637 (-)



Homology
more
  • Human Ortholog
    ECI2, enoyl-CoA delta isomerase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ECI2, enoyl-CoA delta isomerase 2
  • Synonyms
    ACBD2, dJ1013A10.3, DRS-1, DRS1, HCA88, PECI
  • Links
    NCBI Gene ID: 10455
    neXtProt AC: NX_O75521
    UniProt: O75521

  • Chr Location
    6p25.2; chr6:4115693-4135597 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    959
  • Tissues
    208
  • cDNA Data
    148
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021417 Ensembl Gene Model | MGI Sequence Detail 49349 C57BL/6J ±  kb
transcript ENSMUST00000171229 Ensembl | MGI Sequence Detail 1426 Not Applicable  
polypeptide ENSMUSP00000131735 Ensembl | MGI Sequence Detail 391 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000012534 enoyl-CoA Delta isomerase 2
    (term hierarchy)
  • EC
    5.3.3.8
  • InterPro Domains
    IPR000582 Acyl-CoA-binding protein, ACBP
    IPR022408 Acyl-CoA-binding protein, ACBP, conserved site
    IPR035984 Acyl-CoA binding protein superfamily
    IPR029045 ClpP/crotonase-like domain superfamily
    IPR014748 Enoyl-CoA hydratase, C-terminal
    IPR001753 Enoyl-CoA hydratase/isomerase
    IPR051053 Enoyl-CoA hydratase/isomerase and chromodomain-containing protein
    IPR014352 FERM/acyl-CoA-binding protein superfamily
  • GlyGen
    Q9WUR2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 150
    cDNA 149
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory