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Foxb2 Gene Detail
Summary
  • Symbol
    Foxb2
  • Name
    forkhead box B2
  • Synonyms
    Fkh4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347468
    NCBI Gene: 14240
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr19:16849683-16851169 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 12.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347468
 protein coding gene Chr19:16849680-16851194 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024961
 protein coding gene Chr19:14661997-14663511 (-)
A/J MGP_AJ_G0024938
 protein coding gene Chr19:13804490-13806004 (-)
AKR/J MGP_AKRJ_G0024908
 protein coding gene Chr19:14359513-14361027 (-)
BALB/cJ MGP_BALBcJ_G0024937
 protein coding gene Chr19:13840344-13841858 (-)
C3H/HeJ MGP_C3HHeJ_G0024695
 protein coding gene Chr19:14306595-14308109 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025379
 protein coding gene Chr19:15220951-15222465 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022798
 protein coding gene Chr19:14234066-14235580 (-)
CAST/EiJ MGP_CASTEiJ_G0024163
 protein coding gene Chr19:13902615-13904129 (-)
CBA/J MGP_CBAJ_G0024673
 protein coding gene Chr19:15709639-15711147 (-)
DBA/2J MGP_DBA2J_G0024805
 protein coding gene Chr19:13842018-13843526 (-)
FVB/NJ MGP_FVBNJ_G0024766
 protein coding gene Chr19:13767784-13769298 (-)
LP/J MGP_LPJ_G0024889
 protein coding gene Chr19:14640905-14642419 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024793
 protein coding gene Chr19:15656568-15658082 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025434
 protein coding gene Chr19:14284640-14286154 (-)
PWK/PhJ MGP_PWKPhJ_G0023912
 protein coding gene Chr19:13368184-13369695 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023717
 protein coding gene Chr19:13585288-13586802 (-)
WSB/EiJ MGP_WSBEiJ_G0024231
 protein coding gene Chr19:14322808-14324322 (-)



Homology
more
  • Human Ortholog
    FOXB2, forkhead box B2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FOXB2, forkhead box B2
  • Synonyms
    bA159H20.4, FKH4
  • Links
    NCBI Gene ID: 442425
    neXtProt AC: NX_Q5VYV0
    UniProt: Q5VYV0

  • Chr Location
    9q21.2; chr9:77019655-77020953 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    858
  • Tissues
    146
  • cDNA Data
    10
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056829 Ensembl Gene Model | MGI Sequence Detail 1487 C57BL/6J ±  kb
transcript ENSMUST00000072915 Ensembl | MGI Sequence Detail 1487 Not Applicable  
polypeptide ENSMUSP00000072687 Ensembl | MGI Sequence Detail 428 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 11
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-9816, MGI:95547
References
more
  • Summaries
    All 30
    Developmental Gene Expression 9
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:14165 Kaestner KH, et al., Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory