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St6galnac5 Gene Detail
Summary
  • Symbol
    St6galnac5
  • Name
    ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
  • Synonyms
    Siat7e, ST6GalNAc V
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349471
    NCBI Gene: 26938
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:152525522-152687847 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 77.16 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5311 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349471
 protein coding gene Chr3:152522718-152687883 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027995
 protein coding gene Chr3:156704469-156881539 (-)
A/J MGP_AJ_G0027954
 protein coding gene Chr3:151015676-151182217 (-)
AKR/J MGP_AKRJ_G0027920
 protein coding gene Chr3:155019687-155194556 (-)
BALB/cJ MGP_BALBcJ_G0027966
 protein coding gene Chr3:150826367-150994422 (-)
C3H/HeJ MGP_C3HHeJ_G0027696
 protein coding gene Chr3:155435192-155602925 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028409
 protein coding gene Chr3:161847834-162020352 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025747
 protein coding gene Chr3:145820609-145989261 (-)
CAST/EiJ MGP_CASTEiJ_G0027149
 protein coding gene Chr3:155509908-155687735 (-)
CBA/J MGP_CBAJ_G0027671
 protein coding gene Chr3:167675678-167845076 (-)
DBA/2J MGP_DBA2J_G0027811
 protein coding gene Chr3:150113407-150278678 (-)
FVB/NJ MGP_FVBNJ_G0027778
 protein coding gene Chr3:147484853-147649317 (-)
LP/J MGP_LPJ_G0027922
 protein coding gene Chr3:158059939-158232716 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027811
 protein coding gene Chr3:176197394-176370294 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028468
 protein coding gene Chr3:154683260-154853275 (-)
PWK/PhJ MGP_PWKPhJ_G0026872
 protein coding gene Chr3:150009539-150177688 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026700
 protein coding gene Chr3:152828086-153004713 (-)
WSB/EiJ MGP_WSBEiJ_G0027229
 protein coding gene Chr3:155673653-155847089 (-)



Homology
more
  • Human Ortholog
    ST6GALNAC5, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ST6GALNAC5, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
  • Synonyms
    SIAT7-E, SIAT7E, ST6GalNAcV
  • Links
    NCBI Gene ID: 81849
    neXtProt AC: NX_Q9BVH7
    UniProt: Q9BVH7

  • Chr Location
    1p31.1; chr1:76867480-77067546 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1043
  • Tissues
    115
  • cDNA Data
    16
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26938 NCBI Gene Model | MGI Sequence Detail 162326 C57BL/6J ±  kb
transcript NM_012028 RefSeq | MGI Sequence Detail 2827 C57BL/6  
polypeptide Q9QYJ1 UniProt | EBI | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139825
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:58142 Okajima T, et al., Molecular cloning of brain-specific GD1alpha synthase (ST6GalNAc V) containing CAG/Glutamine repeats [published erratum appears in J Biol Chem 2000 Jan 14;275(2):1520]. J Biol Chem. 1999 Oct 22;274(43):30557-62
  • Latest
    J:252096 Paul A, et al., Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity. Cell. 2017 Oct 19;171(3):522-539.e20
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory