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Rps3 Gene Detail
Summary
  • Symbol
    Rps3
  • Name
    ribosomal protein S3
  • Synonyms
    D7Ertd795e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1350917
    NCBI Gene: 27050
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:99127103-99132916 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.07 cM, cytoband F1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    345 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350917
 protein coding gene Chr7:99127103-99132945 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032551
 protein coding gene Chr7:102278105-102283935 (-)
A/J MGP_AJ_G0032525
 protein coding gene Chr7:99731495-99737325 (-)
AKR/J MGP_AKRJ_G0032461
 protein coding gene Chr7:102095084-102100914 (-)
BALB/cJ MGP_BALBcJ_G0032536
 protein coding gene Chr7:99412774-99418604 (-)
C3H/HeJ MGP_C3HHeJ_G0032251
 protein coding gene Chr7:102450255-102456193 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033034
 protein coding gene Chr7:106187560-106193404 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030029
 protein coding gene Chr7:102157125-102162959 (-)
CAST/EiJ MGP_CASTEiJ_G0031578
 protein coding gene Chr7:93995062-94001092 (-)
CBA/J MGP_CBAJ_G0032218
 protein coding gene Chr7:109824469-109830405 (-)
DBA/2J MGP_DBA2J_G0032370
 protein coding gene Chr7:98064417-98070357 (-)
FVB/NJ MGP_FVBNJ_G0032327
 protein coding gene Chr7:97858868-97864698 (-)
LP/J MGP_LPJ_G0032459
 protein coding gene Chr7:103591300-103597130 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032359
 protein coding gene Chr7:111284332-111290144 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033056
 protein coding gene Chr7:101372758-101378597 (-)
PWK/PhJ MGP_PWKPhJ_G0031296
 protein coding gene Chr7:91159450-91165415 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031139
 protein coding gene Chr7:88670800-88676723 (-)
WSB/EiJ MGP_WSBEiJ_G0031695
 protein coding gene Chr7:102036921-102042750 (-)



Homology
more
  • Human Ortholog
    RPS3, ribosomal protein S3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPS3, ribosomal protein S3
  • Synonyms
    S3, uS3
  • Links
    NCBI Gene ID: 6188
    neXtProt AC: NX_P23396
    UniProt: P23396

  • Chr Location
    11q13.4; chr11:75399515-75422302 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    26
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    22
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Rps3
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    25 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    102
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    5
  • cDNA Data
    987
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 27050 NCBI Gene Model | MGI Sequence Detail 5814 C57BL/6J ±  kb
transcript NM_012052 RefSeq | MGI Sequence Detail 1879 ZRU/MplStud  
polypeptide P62908 UniProt | EBI | MGI Sequence Detail 243 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000014275 eukaryotic-type small ribosomal subunit protein uS3
    (term hierarchy)
  • PDB
    7CPU, 7CPV, 7LS1, 7LS2
  • EC
    4.2.99.18
  • InterPro Domains
    IPR015946 K homology domain-like, alpha/beta
    IPR009019 K homology domain superfamily, prokaryotic type
    IPR004044 K Homology domain, type 2
    IPR036419 Ribosomal protein S3, C-terminal domain superfamily
    IPR018280 Small ribosomal subunit protein uS3, conserved site
    IPR001351 Small ribosomal subunit protein uS3, C-terminal
    IPR005703 Small ribosomal subunit protein uS3, eukaryotic/archaeal
  • GlyGen
    P62908 2 sites, 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 988
    cDNA 987
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1289204
References
more
  • Summaries
    All 65
    Developmental Gene Expression 5
    Gene Ontology 15
    Phenotypes 16
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory