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Mrpl17 Gene Detail
Summary
  • Symbol
    Mrpl17
  • Name
    mitochondrial ribosomal protein L17
  • Synonyms
    MRP-L26, Rpml26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351608
    NCBI Gene: 27397
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:105452989-105460294 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 55.98 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    233 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351608
 protein coding gene Chr7:105452413-105460306 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032766
 protein coding gene Chr7:109077320-109081761 (-)
A/J MGP_AJ_G0032746
 protein coding gene Chr7:106230869-106235310 (-)
AKR/J MGP_AKRJ_G0032679
 protein coding gene Chr7:108995189-108999630 (-)
BALB/cJ MGP_BALBcJ_G0032752
 protein coding gene Chr7:105934926-105939367 (-)
C3H/HeJ MGP_C3HHeJ_G0032461
 protein coding gene Chr7:109108198-109112639 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033257
 protein coding gene Chr7:113441022-113445463 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030241
 protein coding gene Chr7:108193853-108198264 (-)
CAST/EiJ MGP_CASTEiJ_G0031791
 protein coding gene Chr7:100938420-100942838 (-)
CBA/J MGP_CBAJ_G0032435
 protein coding gene Chr7:117215459-117219900 (-)
DBA/2J MGP_DBA2J_G0032588
 protein coding gene Chr7:104487075-104491516 (-)
FVB/NJ MGP_FVBNJ_G0032541
 protein coding gene Chr7:104297586-104302027 (-)
LP/J MGP_LPJ_G0032679
 protein coding gene Chr7:110482765-110487206 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032573
 protein coding gene Chr7:118793088-118797515 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033278
 protein coding gene Chr7:108068489-108072901 (-)
PWK/PhJ MGP_PWKPhJ_G0031504
 protein coding gene Chr7:97431650-97436692 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031353
 protein coding gene Chr7:95176277-95180697 (-)
WSB/EiJ MGP_WSBEiJ_G0031908
 protein coding gene Chr7:108703909-108708333 (-)



Homology
more
  • Human Ortholog
    MRPL17, mitochondrial ribosomal protein L17
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL17, mitochondrial ribosomal protein L17
  • Synonyms
    bL17m, L17mt, LIP2, MRP-L17, MRP-L26, RPL17L, RPML26
  • Links
    NCBI Gene ID: 63875
    neXtProt AC: NX_Q9NRX2
    UniProt: Q9NRX2

  • Chr Location
    11p15.4; chr11:6680385-6683340 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Mrpl17
  • Find Mice (IMSR)
    5 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    878
  • Tissues
    31
  • cDNA Data
    16
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 27397 NCBI Gene Model | MGI Sequence Detail 7306 C57BL/6J ±  kb
transcript NM_025301 RefSeq | MGI Sequence Detail 6712 C57BL/6  
polypeptide Q9D8P4 UniProt | EBI | MGI Sequence Detail 176 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010579 large ribosomal subunit protein bL17m
    (term hierarchy)
  • InterPro Domains
    IPR000456 Large ribosomal subunit protein bL17
    IPR036373 Large ribosomal subunit protein bL17 superfamily
  • GlyGen
    Q9D8P4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 18
    cDNA 16
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 46
    Developmental Gene Expression 6
    Gene Ontology 9
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:354661 He XD, et al., Overlapping peri-implantation phenotypes of ZNHIT1 and ZNHIT2 despite distinct functions during early mouse development. Biol Reprod. 2024 Aug 28;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory