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Mrpl15 Gene Detail
Summary
  • Symbol
    Mrpl15
  • Name
    mitochondrial ribosomal protein L15
  • Synonyms
    HSPC145, MRP-L7, Rpml7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351639
    NCBI Gene: 27395
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:4843432-4855949 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 1.79 cM, cytoband A1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    510 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351639
 protein coding gene Chr1:4843429-4855962 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015810
 protein coding gene Chr1:1808646-1821272 (-)
A/J MGP_AJ_G0015792
 protein coding gene Chr1:1885097-1898127 (-)
AKR/J MGP_AKRJ_G0015751
 protein coding gene Chr1:1864272-1876779 (-)
BALB/cJ MGP_BALBcJ_G0015748
 protein coding gene Chr1:1815941-1828476 (-)
C3H/HeJ MGP_C3HHeJ_G0015582
 protein coding gene Chr1:1846523-1858857 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016200
 protein coding gene Chr1:1901332-1920220 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013922
 protein coding gene Chr1:1573684-1584352 (-)
CAST/EiJ MGP_CASTEiJ_G0015162
 protein coding gene Chr1:2018239-2033220 (-)
CBA/J MGP_CBAJ_G0015556
 protein coding gene Chr1:2028898-2041335 (-)
DBA/2J MGP_DBA2J_G0015654
 protein coding gene Chr1:1795521-1809733 (-)
FVB/NJ MGP_FVBNJ_G0015659
 protein coding gene Chr1:1765106-1778283 (-)
LP/J MGP_LPJ_G0015727
 protein coding gene Chr1:1987140-2001369 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015678
 protein coding gene Chr1:2186060-2198372 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016247
 protein coding gene Chr1:1819572-1832156 (-)
PWK/PhJ MGP_PWKPhJ_G0014946
 protein coding gene Chr1:1727719-1740158 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014726
 protein coding gene Chr1:2004362-2016987 (-)
WSB/EiJ MGP_WSBEiJ_G0015226
 protein coding gene Chr1:1820681-1835573 (-)



Homology
more
  • Human Ortholog
    MRPL15, mitochondrial ribosomal protein L15
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL15, mitochondrial ribosomal protein L15
  • Synonyms
    HSPC145, L15mt, MRP-L15, MRP-L7, RPML7, uL15m
  • Links
    NCBI Gene ID: 29088
    neXtProt AC: NX_Q9P015
    UniProt: Q9P015

  • Chr Location
    8q11.23; chr8:54135241-54148514 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    819
  • Tissues
    51
  • cDNA Data
    100
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27395 NCBI Gene Model | MGI Sequence Detail 12518 C57BL/6J ±  kb
transcript NM_001177658 RefSeq | MGI Sequence Detail 4192 C57BL/6  
polypeptide Q9CPR5 UniProt | EBI | MGI Sequence Detail 295 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010577 large ribosomal subunit protein uL15m
    (term hierarchy)
  • InterPro Domains
    IPR030878 Large ribosomal subunit protein uL15
    IPR005749 Large ribosomal subunit protein uL15, bacterial-type
    IPR021131 Large ribosomal subunit protein uL15/eL18
    IPR036227 Large ribosomal subunit protein uL15/eL18 superfamily
Molecular
Reagents
less
  • All nucleic 102
    cDNA 101
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:58917 O'Brien TW, et al., Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences. J Biol Chem. 1999 Dec 17;274(51):36043-51
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory