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Tbl2 Gene Detail
Summary
  • Symbol
    Tbl2
  • Name
    transducin (beta)-like 2
  • Synonyms
    C76179, WS-bTRP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351652
    NCBI Gene: 27368
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:135178288-135192727 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 75.02 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    322 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351652
 protein coding gene Chr5:135178288-135194614 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030175
 protein coding gene Chr5:139651240-139667266 (+)
A/J MGP_AJ_G0030143
 protein coding gene Chr5:133676286-133693274 (+)
AKR/J MGP_AKRJ_G0030076
 protein coding gene Chr5:138023461-138039272 (+)
BALB/cJ MGP_BALBcJ_G0030153
 protein coding gene Chr5:135035068-135051126 (+)
C3H/HeJ MGP_C3HHeJ_G0029869
 protein coding gene Chr5:138585501-138601504 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030606
 protein coding gene Chr5:144879071-144897710 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027829
 protein coding gene Chr5:127970193-127982569 (+)
CAST/EiJ MGP_CASTEiJ_G0029278
 protein coding gene Chr5:138000933-138016789 (+)
CBA/J MGP_CBAJ_G0029839
 protein coding gene Chr5:150554034-150570076 (+)
DBA/2J MGP_DBA2J_G0029990
 protein coding gene Chr5:133578400-133594892 (+)
FVB/NJ MGP_FVBNJ_G0029945
 protein coding gene Chr5:132712173-132729505 (+)
LP/J MGP_LPJ_G0030078
 protein coding gene Chr5:140097803-140113566 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029977
 protein coding gene Chr5:153564308-153580100 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030646
 protein coding gene Chr5:137765993-137784299 (+)
PWK/PhJ MGP_PWKPhJ_G0028993
 protein coding gene Chr5:132620906-132637073 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028828
 protein coding gene Chr5:135333567-135349386 (+)
WSB/EiJ MGP_WSBEiJ_G0029352
 protein coding gene Chr5:138520714-138536664 (+)



Homology
more
  • Human Ortholog
    TBL2, transducin beta like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TBL2, transducin beta like 2
  • Synonyms
    WBSCR13, WS-betaTRP
  • Links
    NCBI Gene ID: 26608
    neXtProt AC: NX_Q9Y4P3
    UniProt: Q9Y4P3

  • Chr Location
    7q11.23; chr7:73567537-73578791 (-)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27368 NCBI Gene Model | MGI Sequence Detail 14440 C57BL/6J ±  kb
transcript NM_013763 RefSeq | MGI Sequence Detail 5588 C57BL/6  
polypeptide Q9R099 UniProt | EBI | MGI Sequence Detail 442 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 5
    cDNA 13
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:2141271
References
more
  • Summaries
    All 48
    Diseases 2
    Gene Ontology 3
    Phenotypes 20
  • Earliest
    J:58545 Perez Jurado LA, et al., TBL2, a novel transducin family member in the WBS deletion: characterization of the complete sequence, genomic structure, transcriptional variants and the mouse ortholog. Cytogenet Cell Genet. 1999;86(3-4):277-84
  • Latest
    J:337436 Abdalla N, et al., Dysfunctional Mitochondria in the Cardiac Fibers of a Williams-Beuren Syndrome Mouse Model. Int J Mol Sci. 2023 Jun 13;24(12)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory